Quercetin is a flavonoid abundantly found in fruits and vegetables. It possesses a wide
spectrum of biological activities, thus suggesting a role in disease prevention and health …

Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

In the physiological condition, the skeletal system's bone resorption and formation are in
dynamic balance, called bone homeostasis. However, bone homeostasis is destroyed under …

The process of repairing significant bone defects requires the recruitment of a considerable
number of cells for osteogenesis-related activities, which implies the consumption of a …

The hypoxia pathway not only regulates the organism to adapt to the special environment,
such as short-term hypoxia in the plateau under normal physiological conditions, but also …

Bone reconstruction includes a steady state system of bone formation and bone absorption.
This tight coupling requires subtle coordination between osteoblasts and osteoclasts. If this …

The imbalance of bone homeostasis has become a major public medical problem amid the
background of an aging population, which is closely related to the occurrence of …

Hypoxia at high-altitude leads to osteoporosis. Resveratrol (RES), as an antioxidant, has
been reported to promote osteoblastogenesis and suppress osteoclastogenesis. However …

Parkinson's disease is the second most common neurodegenerative disease. Researchers
have shown that oxidative stress and apoptosis play an important role in the Parkinson's …

Inflammatory response contributes to brain injury after ischemia and reperfusion (I/R). Our
previous literature has shown isoquercetin plays an important role in protecting against …