Oligodendrocyte, astrocyte, and microglia crosstalk in myelin development, damage, and repair
Oligodendrocytes are the myelinating glia of the central nervous system. Myelination of
axons allows rapid saltatory conduction of nerve impulses and contributes to axonal …
axons allows rapid saltatory conduction of nerve impulses and contributes to axonal …
Microglia: architects of the developing nervous system
JL Frost, DP Schafer - Trends in cell biology, 2016 - cell.com
Microglia are resident macrophages of the central nervous system (CNS), representing 5–
10% of total CNS cells. Recent findings reveal that microglia enter the embryonic brain, take …
10% of total CNS cells. Recent findings reveal that microglia enter the embryonic brain, take …
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model
P Zhang, Y Kishimoto, I Grammatikakis… - Nature …, 2019 - nature.com
Neuritic plaques, a pathological hallmark in Alzheimer's disease (AD) brains, comprise
extracellular aggregates of amyloid-beta (Aβ) peptide and degenerating neurites that …
extracellular aggregates of amyloid-beta (Aβ) peptide and degenerating neurites that …
Glia as sculptors of synaptic plasticity
L Sancho, M Contreras, NJ Allen - Neuroscience Research, 2021 - Elsevier
Glial cells are non-neuronal cells in the nervous system that are crucial for proper brain
development and function. Three major classes of glia in the central nervous system (CNS) …
development and function. Three major classes of glia in the central nervous system (CNS) …
Aging of cerebral white matter
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …
The pathophysiological role of microglia in dynamic surveillance, phagocytosis and structural remodeling of the developing CNS
In vertebrates, during an early wave of hematopoiesis in the yolk sac between embryonic
day E7. 0 and E9. 0, cells of mesodermal leaflet addressed to macrophage lineage enter in …
day E7. 0 and E9. 0, cells of mesodermal leaflet addressed to macrophage lineage enter in …
Astrocytes and microglia as major players of myelin production in normal and pathological conditions
E Traiffort, A Kassoussi, A Zahaf… - Frontiers in Cellular …, 2020 - frontiersin.org
Myelination is an essential process that consists of the ensheathment of axons by myelin. In
the central nervous system (CNS), myelin is synthesized by oligodendrocytes. The …
the central nervous system (CNS), myelin is synthesized by oligodendrocytes. The …
Iron metabolism in oligodendrocytes and astrocytes, implications for myelination and remyelination
Iron is a key nutrient for normal central nervous system (CNS) development and function;
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …
Astrocyte and oligodendrocyte cross-talk in the central nervous system
E Nutma, D van Gent, S Amor, LAN Peferoen - Cells, 2020 - mdpi.com
Over the last decade knowledge of the role of astrocytes in central nervous system (CNS)
neuroinflammatory diseases has changed dramatically. Rather than playing a merely …
neuroinflammatory diseases has changed dramatically. Rather than playing a merely …
Glial cells in glaucoma: friends, foes, and potential therapeutic targets
MY García-Bermúdez, KK Freude… - Frontiers in …, 2021 - frontiersin.org
Glaucoma is the second leading cause of blindness worldwide, affecting~ 80 million people
by 2020 (,). The condition is characterized by a progressive loss of retinal ganglion cells …
by 2020 (,). The condition is characterized by a progressive loss of retinal ganglion cells …