Hepatocellular carcinoma is a leading cancer worldwide. Its incidence is increasing, and is
closely related to advanced liver disease. Cirrhosis represents the greatest risk factor for this …

Telomerase is a key enzyme for cell survival that prevents telomere shortening and the
subsequent cellular senescence that is observed after many rounds of cell division. In …

中国人群的肝癌存在生存率低, 死亡率高的情况, 如何有效降低肝癌相关负担仍是中国公共卫生
和慢性病防控领域亟待解决的重大问题, 而肝癌人群筛查策略优化是值得持续探索的重要抓手和 …

EASL–EORTC Clinical Practice Guidelines (CPG) on the management of hepatocellular
carcinoma (HCC) define the use of surveillance, diagnosis, and therapeutic strategies …

EASL–EORTC Clinical Practice Guidelines (CPG) on the management of hepatocellular
carcinoma (HCC) define the use of surveillance, diagnosis, and therapeutic strategies …

Emerging data indicate that the mortality rate of hepatocellular carcinoma (HCC) associated
with cirrhosis is rising in some developed countries, whereas mortality from non-HCC …

Tumor infiltrated type II (M2) macrophages promote tumorigenesis by suppressing immune
clearance, promoting proliferation, and stimulating angiogenesis. Interestingly …

Genetic determinants of the early steps of carcinogenesis on cirrhosis are still poorly
understood. We aimed to evaluate the occurrence of telomerase reverse transcriptase …

Background & Aims: Because the efficacy of UDCA on long-term outcome of primary biliary
cirrhosis (PBC) has not been completely elucidated, we have assessed the course and …

Angiogenesis and disruption of liver vascular architecture have been linked to progression
to cirrhosis and liver cancer (HCC) in chronic liver diseases, which contributes both to …