Muscle and cardiac therapeutic strategies for Duchenne muscular dystrophy: past, present, and future

A Łoboda, J Dulak - Pharmacological Reports, 2020 - Springer
Background Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular
childhood disorder that causes progressive muscle weakness and degeneration and results …

Adipose-derived mesenchymal stem cells: a promising tool in the treatment of musculoskeletal diseases

M Torres-Torrillas, M Rubio, E Damia, B Cuervo… - International Journal of …, 2019 - mdpi.com
Chronic musculoskeletal (MSK) pain is one of the most common medical complaints
worldwide and musculoskeletal injuries have an enormous social and economical impact …

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages

J Liu, X Qiu, Y Lv, C Zheng, Y Dong, G Dou… - Stem cell research & …, 2020 - Springer
Background As the major interface between the body and the external environment, the skin
is liable to various injuries. Skin injuries often lead to severe disability, and the exploration of …

Exosomal miR-499a-5p inhibits endometrial cancer growth and metastasis via targeting VAV3

L Jing, X Hua, D Yuanna, Z Rukun… - Cancer Management …, 2020 - Taylor & Francis
Background/Aim The current therapeutic strategies for endometrial cancer are limited and
unsatisfactory. Accumulating evidence suggest that microRNAs (miRNAs) participate in …

Nerve growth factor (NGF) and NGF receptors in mesenchymal stem/stromal cells: Impact on potential therapies

K Zha, Y Yang, G Tian, Z Sun, Z Yang… - Stem cells …, 2021 - academic.oup.com
Mesenchymal stem/stromal cells (MSCs) are promising for the treatment of degenerative
diseases and traumatic injuries. However, MSC engraftment is not always successful and …

The effect of culture media on large-scale expansion and characteristic of adipose tissue-derived mesenchymal stromal cells

J Czapla, S Matuszczak, K Kulik, E Wiśniewska… - Stem cell research & …, 2019 - Springer
Background Adipose tissue-derived mesenchymal stromal cells (ASCs) have been shown to
exhibit some promising properties of their use in regenerative medicine as advanced …

Cargo proteins in extracellular vesicles: potential for novel therapeutics in non-alcoholic steatohepatitis

J Kim, SK Lee, SY Jeong, HJ Cho, J Park… - Journal of …, 2021 - Springer
Abstract Background Extracellular vesicles (EVs) are recognized as novel cell-free
therapeutics. Non-alcoholic steatohepatitis (NASH) remains a critical health problem …

Mechanisms behind the immunoregulatory dialogue between mesenchymal stem cells and Th17 cells

C Terraza-Aguirre, M Campos-Mora, R Elizondo-Vega… - Cells, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) exhibit potent immunoregulatory abilities by interacting
with cells of the adaptive and innate immune system. In vitro, MSCs inhibit the differentiation …

The blood circulating rare cell population. What is it and what is it good for?

S Schreier, W Triampo - Cells, 2020 - mdpi.com
Blood contains a diverse cell population of low concentration hematopoietic as well as non-
hematopoietic cells. The majority of such rare cells may be bone marrow-derived progenitor …

Human induced pluripotent stem cell-derived cardiomyocytes, in contrast to adipose tissue-derived stromal cells, efficiently improve heart function in murine model of …

J Stępniewski, M Tomczyk, K Andrysiak, I Kraszewska… - Biomedicines, 2020 - mdpi.com
Cell therapies are extensively tested to restore heart function after myocardial infarction (MI).
Survival of any cell type after intracardiac administration, however, may be limited due to …