Surface coatings for solid-state nanopores

OM Eggenberger, C Ying, M Mayer - Nanoscale, 2019 - pubs.rsc.org
Since their introduction in 2001, solid-state nanopores have been increasingly exploited for
the detection and characterization of biomolecules ranging from single DNA strands to …

Fabrication and applications of solid-state nanopores

Q Chen, Z Liu - Sensors, 2019 - mdpi.com
Nanopores fabricated from synthetic materials (solid-state nanopores), platforms for
characterizing biological molecules, have been widely studied among researchers …

Electroosmotic trap against the electrophoretic force near a protein nanopore reveals peptide dynamics during capture and translocation

A Asandei, I Schiopu, M Chinappi, CH Seo… - … applied materials & …, 2016 - ACS Publications
We report on the ability to control the dynamics of a single peptide capture and passage
across a voltage-biased, α-hemolysin nanopore (α-HL), under conditions that the …

Protein sequencing via nanopore based devices: a nanofluidics perspective

M Chinappi, F Cecconi - Journal of Physics: Condensed Matter, 2018 - iopscience.iop.org
Proteins perform a huge number of central functions in living organisms, thus all the new
techniques allowing their precise, fast and accurate characterization at single-molecule level …

Translocation frequency of double-stranded DNA through a solid-state nanopore

NAW Bell, M Muthukumar, UF Keyser - Physical Review E, 2016 - APS
Solid-state nanopores are single-molecule sensors that measure changes in ionic current as
charged polymers such as DNA pass through. Here, we present comprehensive …

Particle trajectory-dependent ionic current blockade in low-aspect-ratio pores

M Tsutsui, Y He, K Yokota, A Arima, S Hongo… - ACS …, 2016 - ACS Publications
Resistive pulse sensing with nanopores having a low thickness-to-diameter aspect-ratio
structure is expected to enable high-spatial-resolution analysis of nanoscale objects in a …

Current enhancement in solid-state nanopores depends on three-dimensional DNA structure

V Wang, N Ermann, UF Keyser - Nano Letters, 2019 - ACS Publications
The translocation of double-stranded DNA through a solid-state nanopore may either
decrease or increase the ionic current depending on the ionic concentration of the …

Accurate modeling of a biological nanopore with an extended continuum framework

K Willems, D Ruić, FLR Lucas, U Barman, N Verellen… - Nanoscale, 2020 - pubs.rsc.org
Despite the broad success of biological nanopores as powerful instruments for the analysis
of proteins and nucleic acids at the single-molecule level, a fast simulation methodology to …

Placement of oppositely charged aminoacids at a polypeptide termini determines the voltage-controlled braking of polymer transport through nanometer-scale pores

A Asandei, M Chinappi, J Lee, C Ho Seo, L Mereuta… - Scientific reports, 2015 - nature.com
Protein and solid-state nanometer-scale pores are being developed for the detection,
analysis and manipulation of single molecules. In the simplest embodiment, the entry of a …

Translocation of rigid rod-shaped virus through various solid-state nanopores

H Wu, Y Chen, Q Zhou, R Wang, B Xia, D Ma… - Analytical …, 2016 - ACS Publications
Nanopores have been used as a high throughput tool for characterizing individual
biomolecules and nanoparticles. Here, we present the translocation of rigid rod-shaped …