Structure and function of lamellar bodies, lipid-protein complexes involved in storage and secretion of cellular lipids.

G Schmitz, G Müller - Journal of lipid research, 1991 - ASBMB
This review article attempts to present an overview of the occurrence and function of lipid
storage and secretory organelles: the lamellar bodies. Morphologically these organelles …

Hydrophobic surfactant proteins in lung function and disease

JA Whitsett, TE Weaver - New England Journal of Medicine, 2002 - Mass Medical Soc
Pulmonary surfactants consist of phospholipids and the hydrophobic proteins surfactant
protein B and surfactant protein C. These surfactants keep the alveoli in the lung open to the …

Biosurfactants: moving towards industrial application

A Fiechter - Trends in biotechnology, 1992 - Elsevier
Chemically synthesized surface-active compounds are widely used in the pharmaceutical,
cosmetic, petroleum and food industries. However, with the advantages of biodegradability …

[图书][B] Lung surfactants: basic science and clinical applications

RH Notter - 2000 - api.taylorfrancis.com
Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

[HTML][HTML] Role of pulmonary surfactant components in surface film formation and dynamics

EJA Veldhuizen, HP Haagsman - Biochimica et biophysica acta (bba) …, 2000 - Elsevier
Pulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial
type II cells into the alveolar space. Its main function is to reduce the surface tension at the …

Function and regulation of expression of pulmonary surfactant-associated proteins.

TE Weaver, JA Whitsett - Biochemical journal, 1991 - ncbi.nlm.nih.gov
Pulmonary surfactant is composed of approximately 90% lipid, 10% protein and small
amounts ofcarbohydrate. Dipalmitoylphosphatidylcholine (DPPC), which accounts for …

The pulmonary surfactant system: biochemical and clinical aspects

L Creuwels, LMG Van Golde, HP Haagsman - Lung, 1997 - Springer
This article starts with a brief account of the history of research on pulmonary surfactant. We
will then discuss the morphological aspects and composition of the pulmonary surfactant …

Electrospray mass spectrometry of biomacromolecular complexes with noncovalent interactions—new analytical perspectives for supramolecular chemistry and …

M Przybylski, MO Glocker - Angewandte Chemie International …, 1996 - Wiley Online Library
The development of “soft” ionization methods in recent years has enabled substantial
progress in the mass spectrometric characterization of macromolecules, in particular …

Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function

R Qanbar, M Bouvier - Pharmacology & therapeutics, 2003 - Elsevier
G-protein-coupled receptors (GPCRs) constitute one of the largest protein families in the
human genome. They are subject to numerous post-translational modifications, including …

Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration

AA Kapralov, WH Feng, AA Amoscato, N Yanamala… - ACS …, 2012 - ACS Publications
The pulmonary route represents one of the most important portals of entry for nanoparticles
into the body. However, the in vivo interactions of nanoparticles with biomolecules of the …