[HTML][HTML] From obesity-induced low-grade inflammation to lipotoxicity and mitochondrial dysfunction: altered multi-crosstalk between adipose tissue and metabolically …

G Cavaliere, F Cimmino, G Trinchese, A Catapano… - Antioxidants, 2023 - mdpi.com
Obesity is a major risk factor for several metabolic diseases, including type 2 diabetes,
hyperlipidemia, cardiovascular diseases, and brain disorders. Growing evidence suggests …

Early life gut microbiota: consequences for health and opportunities for prevention

S Wang, J Cui, S Jiang, C Zheng, J Zhao… - Critical Reviews in …, 2024 - Taylor & Francis
The gut microbiota influences many aspects of the host, including immune system
maturation, nutrient absorption and metabolism, and protection from pathogens. Increasing …

Airborne Nanoplastics Exposure Inducing Irreversible Glucose Increase and Complete Hepatic Insulin Resistance

Z Yang, H Dong, Y Gao, S Liu, L Chen… - Environmental …, 2024 - ACS Publications
As an emerging type of pollutant, microplastics have become a global environmental
problem. Approximately, a fifth of the global burden of type 2 diabetes can be attributed to air …

[HTML][HTML] Analysis and regulatory mechanisms of platelet-related genes in patients with ischemic stroke

Y Li, Y Shu, K Yu, R Ni, L Chu - Cellular and Molecular Neurobiology, 2024 - Springer
It was found that ischemic stroke (IS) was associated with abnormal platelet activity and
thrombosis. However, the potential significance of platelet-related genes (PRGs) in IS still …

Structural and functional damage to the retina and skeletal muscle in Xenopus laevis embryos exposed to the commonly used psychotropic benzodiazepine …

C Fogliano, R Carotenuto, G Rusciano, A Sasso… - Environmental …, 2023 - Elsevier
Benzodiazepines, psychotropic drugs, are among the most frequently found
pharmaceuticals in aquatic matrices. An increasing number of studies are reporting their …

Untargeted metabolomics reveals hepatic metabolic disorder in the BTBR mouse model of autism and the significant role of liver in autism

C Cao, D Wang, M Zou, C Sun… - Cell Biochemistry and …, 2023 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental disorder, and the etiology is
unknown. Metabolic dysfunction is present in patients with ASD. In the current study …

[HTML][HTML] Potential Neuroprotective Effect of Melatonin in the Hippocampus of Male BTBR Mice

M Bonetti, L Giugno, E Borsani, F Bonomini - Nutrients, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder identified by impairments
in common social interactions and repetitive behaviors. In ASD patients, substantial …

[HTML][HTML] Hepatic Alterations in a BTBR T+ Itpr3tf/J Mouse Model of Autism and Improvement Using Melatonin via Mitigation Oxidative Stress, Inflammation and …

R Rezzani, M Gianò, D Pinto, F Rinaldi… - International Journal of …, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a complicated neurodevelopmental disorder, and its
etiology is not well understood. It is known that genetic and nongenetic factors determine …

[HTML][HTML] Interaction between Per-and Polyfluorinated Substances (PFAS) and Acetaminophen in Disease Exacerbation—Focusing on Autism and the Gut–Liver–Brain …

DQY Jiang, TL Guo - Toxics, 2024 - mdpi.com
This review presents a new perspective on the exacerbation of autism spectrum disorder
(ASD) by per-and polyfluoroalkyl substances (PFAS) through the gut–liver–brain axis. We …

[HTML][HTML] Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T+ Itpr3tf/J Mice

MM Alanazi, MA Ansari, A Nadeem, SM Attia… - International Journal of …, 2023 - mdpi.com
Autism spectrum disorders (ASD) are neurobehavioral disabilities characterized by impaired
social interactions, poor communication skills, and restrictive/repetitive behaviors. Cadmium …