[HTML][HTML] Reactive oxygen species and mitochondria: A nexus of cellular homeostasis
Reactive oxygen species (ROS) are integral components of multiple cellular pathways even
though excessive or inappropriately localized ROS damage cells. ROS function as anti …
though excessive or inappropriately localized ROS damage cells. ROS function as anti …
Mycobacterium marinum
A Aubry, F Mougari, F Reibel… - Tuberculosis and …, 2017 - Wiley Online Library
The first report of a mycobacterium isolated in fish, supposed to be Mycobacterium marinum,
has been attributed to Bataillon et al.(1897), who isolated acid‐fast bacilli named …
has been attributed to Bataillon et al.(1897), who isolated acid‐fast bacilli named …
Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages
E Pellegrino, B Aylan, C Bussi, A Fearns… - Journal of Cell …, 2023 - rupress.org
Peroxisomes are organelles involved in many metabolic processes including lipid
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …
The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection
Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …
Protection and pathology in TB: learning from the zebrafish model
AH Meijer - Seminars in immunopathology, 2016 - Springer
Zebrafish has earned its place among animal models of tuberculosis. Its natural pathogen,
Mycobacterium marinum, shares major virulence factors with the human pathogen …
Mycobacterium marinum, shares major virulence factors with the human pathogen …
Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model
A Mesquita, E Cardenal-Munoz, E Dominguez… - Autophagy, 2017 - Taylor & Francis
Autophagy is a fast-moving field with an enormous impact on human health and disease.
Understanding the complexity of the mechanism and regulation of this process often benefits …
Understanding the complexity of the mechanism and regulation of this process often benefits …
Autophagy regulation in teleost fish: A double-edged sword
Z Zhou, Y He, S Wang, Y Wang, P Shan, P Li - Aquaculture, 2022 - Elsevier
In the last two decades, autophagy has attracted considerable attention as a conserved
cellular self-digestion process that is essential for cells to maintain metabolism and energy …
cellular self-digestion process that is essential for cells to maintain metabolism and energy …
Mycobacterium tuberculosis LprE suppresses TLR2-dependent cathelicidin and autophagy expression to enhance bacterial survival in macrophages
A Padhi, K Pattnaik, M Biswas, M Jagadeb… - The Journal of …, 2019 - journals.aai.org
Despite representing a very important class of virulence proteins, the role of lipoproteins in
the pathogenesis of Mycobacterium tuberculosis remains elusive. In this study, we …
the pathogenesis of Mycobacterium tuberculosis remains elusive. In this study, we …
Studying autophagy in zebrafish
Autophagy is an evolutionarily conserved catabolic process which allows lysosomal
degradation of complex cytoplasmic components into basic biomolecules that are recycled …
degradation of complex cytoplasmic components into basic biomolecules that are recycled …
Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner
E Cardenal-Muñoz, S Arafah, AT López-Jiménez… - PLoS …, 2017 - journals.plos.org
Autophagy is a eukaryotic catabolic process also participating in cell-autonomous defence.
Infected host cells generate double-membrane autophagosomes that mature in …
Infected host cells generate double-membrane autophagosomes that mature in …