[HTML][HTML] Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

JD Dunn, LAJ Alvarez, X Zhang, T Soldati - Redox biology, 2015 - Elsevier
Reactive oxygen species (ROS) are integral components of multiple cellular pathways even
though excessive or inappropriately localized ROS damage cells. ROS function as anti …

Mycobacterium marinum

A Aubry, F Mougari, F Reibel… - Tuberculosis and …, 2017 - Wiley Online Library
The first report of a mycobacterium isolated in fish, supposed to be Mycobacterium marinum,
has been attributed to Bataillon et al.(1897), who isolated acid‐fast bacilli named …

Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages

E Pellegrino, B Aylan, C Bussi, A Fearns… - Journal of Cell …, 2023 - rupress.org
Peroxisomes are organelles involved in many metabolic processes including lipid
metabolism, reactive oxygen species (ROS) turnover, and antimicrobial immune responses …

The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection

M Shariq, N Quadir, A Alam, S Zarin, JA Sheikh… - Autophagy, 2023 - Taylor & Francis
Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …

Protection and pathology in TB: learning from the zebrafish model

AH Meijer - Seminars in immunopathology, 2016 - Springer
Zebrafish has earned its place among animal models of tuberculosis. Its natural pathogen,
Mycobacterium marinum, shares major virulence factors with the human pathogen …

Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model

A Mesquita, E Cardenal-Munoz, E Dominguez… - Autophagy, 2017 - Taylor & Francis
Autophagy is a fast-moving field with an enormous impact on human health and disease.
Understanding the complexity of the mechanism and regulation of this process often benefits …

Autophagy regulation in teleost fish: A double-edged sword

Z Zhou, Y He, S Wang, Y Wang, P Shan, P Li - Aquaculture, 2022 - Elsevier
In the last two decades, autophagy has attracted considerable attention as a conserved
cellular self-digestion process that is essential for cells to maintain metabolism and energy …

Mycobacterium tuberculosis LprE suppresses TLR2-dependent cathelicidin and autophagy expression to enhance bacterial survival in macrophages

A Padhi, K Pattnaik, M Biswas, M Jagadeb… - The Journal of …, 2019 - journals.aai.org
Despite representing a very important class of virulence proteins, the role of lipoproteins in
the pathogenesis of Mycobacterium tuberculosis remains elusive. In this study, we …

Studying autophagy in zebrafish

BJ Mathai, AH Meijer, A Simonsen - Cells, 2017 - mdpi.com
Autophagy is an evolutionarily conserved catabolic process which allows lysosomal
degradation of complex cytoplasmic components into basic biomolecules that are recycled …

Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner

E Cardenal-Muñoz, S Arafah, AT López-Jiménez… - PLoS …, 2017 - journals.plos.org
Autophagy is a eukaryotic catabolic process also participating in cell-autonomous defence.
Infected host cells generate double-membrane autophagosomes that mature in …