Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet

L Malcovati, E Hellström-Lindberg… - Blood, The Journal …, 2013 - ashpublications.org
Within the myelodysplastic syndrome (MDS) work package of the European LeukemiaNet,
an Expert Panel was selected according to the framework elements of the National Institutes …

Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference

P Valent, HP Horny, JM Bennett, C Fonatsch… - Leukemia research, 2007 - Elsevier
The classification, scoring systems, and response criteria for myelodysplastic syndromes
(MDS) have recently been updated and have become widely accepted. In addition, several …

[HTML][HTML] Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis

X Wu, Y Liu, S Jin, M Wang, Y Jiao, B Yang… - Nature …, 2021 - nature.com
The presence or absence of anti-citrullinated peptide antibodies (ACPA) and associated
disparities in patients with rheumatoid arthritis (RA) implies disease heterogeneity with …

Myelodysplastic syndromes, version 2.2017, NCCN clinical practice guidelines in oncology

PL Greenberg, RM Stone, A Al-Kali, SK Barta… - Journal of the National …, 2017 - jnccn.org
The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid
disorders with a highly variable disease course. Diagnostic criteria to better stratify patients …

Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry

MJ Borowitz, FE Craig, JA DiGiuseppe… - Cytometry Part B …, 2010 - Wiley Online Library
Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematopoietic stem cell
disorder characterized by a somatic mutation in the PIGA gene, leading to a deficiency of …

[HTML][HTML] Mutations in TERT, the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia

H Yamaguchi, RT Calado, H Ly… - … England Journal of …, 2005 - Mass Medical Soc
Background Mutations in TERC, the gene for the RNA component of telomerase, cause
short telomeres in congenital aplastic anemia and in some cases of apparently acquired …

Advances in understanding the pathogenesis of acquired aplastic anaemia

L Luzzatto, AM Risitano - British Journal of Haematology, 2018 - Wiley Online Library
This review examines the evidence that bone marrow failure (BMF) in aplastic anaemia (AA)
is due to loss of haematopoietic stem cells (HSC s), which, in turn, is caused by deranged …

Minor population of CD55-CD59- blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia

C Sugimori, T Chuhjo, X Feng, H Yamazaki, A Takami… - Blood, 2006 - ashpublications.org
We investigated the clinical significance of a minor population of paroxysmal nocturnal
hemoglobinuria (PNH)-type blood cells in patients with acquired aplastic anemia (AA). We …

Immunosuppressive therapy for patients with myelodysplastic syndrome: a prospective randomized multicenter phase III trial comparing antithymocyte globulin plus …

JR Passweg, AAN Giagounidis, M Simcock… - Journal of clinical …, 2011 - ascopubs.org
Purpose Immunosuppressive treatment is reported to improve cytopenia in some patients
with myelodysplastic syndrome (MDS). Combined antithymocyte globulin (ATG) and …

Myelodysplastic syndromes

PL Greenberg, E Attar, JM Bennett… - Journal of the National …, 2011 - jnccn.org
Overview T he myelodysplastic syndromes (MDS) represent myeloid clonal hemopathies
with relatively heterogeneous spectrums of presentation. The major clinical problems in …