The 1, 8‐naphthyridine group of compounds have gained special attention of researchers
on account of their demonstrating a variety of interesting biological activities. A wide range of …

Abstract Serotonin (5‐hydroxytryptophan [5‐HT]) is a biologically active amine expressed in
platelets, in gastrointestinal (GI) cells and, to a lesser extent, in the central nervous system …

Antibiotic resistance can be characterized, in biochemical terms, as an antibiotic's inability to
reach its bacterial target at a concentration that was previously effective. Microbial resistance …

1, 8-Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic
compounds which has garnered the interest of researchers due to its versatile biological …

Venlafaxine, a novel third‐generation antidepressant drug, has been described as a
reference treatment for major depression, owing to its ability of inhibiting both noradrenalin …

Speckle-type POZ protein (SPOP) is overexpressed in the nucleus and misallocated in the
cytoplasm in almost all the clear-cell renal cell carcinomas (ccRCCs), which leads to kidney …

The piperazine derivatives correspond to an extensive chemical class of compounds with
numerous neuropharmacological activities, including antidepressant (eg, nefazodone …

naphthyridines are synthesized using a four-component, one-pot approach. This method
includes the reaction of aromatic aldehyde, malononitrile, 1, 6-dimethylpyridin-2 (1H)-one …

Naphthyridines (NAP) are biological important scaffolds in bioactive molecules design. By
hybrid of NAP with neonicotinoid core structure, nine novel NAP derivatives were …

Asthma (ATA) is a long term inflammatory condition of the respiratory tract (RT) where stress
and psychological factors play a significant role. A high rate of comorbidity of ATA and …