Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent
reperfusion of the brain following resuscitation. In those who are admitted to intensive care …

Intracranial pressure (ICP) monitoring is now viewed as integral to the clinical care of many
life-threatening brain insults, such as severe traumatic brain injury, subarachnoid …

Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …

Impaired cerebral autoregulation (CA) in moderate/severe traumatic brain injury (TBI) has
been identified as a strong associate with poor long-term outcomes, with recent data …

Current neurointensive care guidelines recommend intracranial pressure (ICP) and cerebral
perfusion pressure (CPP) centered management for moderate-severe traumatic brain injury …

Abstract Purpose CPPopt denotes a Cerebral Perfusion Pressure (CPP) value at which the
Pressure-Reactivity index, reflecting the global state of Cerebral Autoregulation, is best …

Secondary brain injury after neurotrauma is comprised of a host of distinct, potentially
concurrent and interacting mechanisms that may exacerbate primary brain insult …

Cerebrovascular reactivity defines the ability of the cerebral vasculature to regulate its
resistance in response to both local and systemic factors to ensure an adequate cerebral …

OBJECTIVES: To examine cerebrovascular pressure reactivity index (PRx) in a large cohort
of children with severe traumatic brain injury (sTBI) in association with physiologic variables …