An integrative approach to the pulmonary physiology of exercise: when does biological sex matter?

B Archiza, MG Leahy, S Kipp, AW Sheel - European Journal of Applied …, 2021 - Springer
Historically, many studies investigating the pulmonary physiology of exercise (and
biomedical research in general) were performed exclusively or predominantly with male …

Respiratory muscles during exercise: mechanics, energetics, and fatigue

JF Welch, S Kipp, AW Sheel - Current Opinion in Physiology, 2019 - Elsevier
The respiratory muscles encompass a variety of functions and roles, their action during
exercise facilitates arterial blood-gas and pH regulation. Exercise hyperpnea is the first line …

Impaired central hemodynamics in chronic obstructive pulmonary disease during submaximal exercise

JR Smith, BD Johnson… - Journal of applied …, 2019 - journals.physiology.org
It is unknown whether central hemodynamics are impaired during exercise in chronic
obstructive pulmonary disease (COPD) patients. We hypothesized that, at a similar absolute …

Modelling the effects of age and sex on the resistive and viscoelastic components of the work of breathing during exercise

Y Molgat‐Seon, PB Dominelli… - Experimental …, 2019 - Wiley Online Library
New Findings What is the central question of this study? What is the effect of age and sex on
the resistive and viscoelastic components of work of breathing (Wb) during exercise? What …

A comparison of methods used to quantify the work of breathing during exercise

TJ Cross, EA Gideon, SJ Morris… - Journal of Applied …, 2021 - journals.physiology.org
The mechanical work of breathing (Wb) is an insightful tool used to assess respiratory
mechanics during exercise. There are several different methods used to calculate the Wb …

Ventilatory constraints influence physiological dead space in heart failure

JR Smith, TP Olson - Experimental physiology, 2019 - Wiley Online Library
New Findings What is the central question of this study? The goal of this study was to
investigate the effect of alterations in tidal volume and alveolar volume on the elevated …

THE METABOLIC COST OF BREATHING FOR EXERCISE VENTILATIONS: EFFECTS OF AGE AND SEX

S Kipp, SR Arn, MG Leahy… - Journal of Applied …, 2024 - journals.physiology.org
Given there are both sex-based structural differences in the respiratory system and age-
associated declines in pulmonary function, the purpose of this study was to assess the …

Impact of aging on the work of breathing during exercise in healthy men

JC Weavil, TS Thurston, TJ Hureau… - Journal of Applied …, 2022 - journals.physiology.org
This study examined the impact of aging on the elastic and resistive components of the work
of breathing (W b) during locomotor exercise at a given 1) ventilatory rate, 2) metabolic rate …

[HTML][HTML] Respiratory muscle senescence in ageing and chronic lung diseases

J Gea, P Ausín, JM Martínez-Llorens… - European Respiratory …, 2020 - Eur Respiratory Soc
Ageing is a progressive condition that usually leads to the loss of physiological properties.
This process is also present in respiratory muscles, which are affected by both senescent …

Tidal volume expandability affected by flow, dynamic hyperinflation, and quasi-fixed inspiratory time in patients with COPD and healthy individuals

ML Chuang - Chronic Respiratory Disease, 2022 - journals.sagepub.com
Exertional dyspnea (ED) and impaired exercise performance (EP) are mainly caused by
dynamic hyperinflation (DH) in chronic obstructive pulmonary disease (COPD) patients by …