Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate
direct intercellular communication, a critical feature for the development, function, and …

Gap junctions contain cell–cell communicating channels that consist of multimeric proteins
called connexins and mediate the exchange of low-molecular-weight metabolites and ions …

Gap junctions are specialized cell–cell junctions that directly link the cytoplasm of
neighboring cells. They mediate the direct transfer of metabolites and ions from one cell to …

Background—A common single-nucleotide polymorphism (SNP) in the promoter of the
Connexin-40 (Cx40) gene GJA5 was suggested to affect Cx40 promoter activity and the risk …

Vascular endothelial cells (ECs) play a major role in regulating vascular tone and in
revascularization. There is increasing evidence showing endothelial dysfunction in diabetes …

The connexin genes code for a family of proteins that form intercellular gap junction
channels. There are 21 connexin genes in the human genome and 20 in the mouse …

Connexins (Cxs) form a family of transmembrane proteins comprising 21 members in
humans. Cxs differ in their expression patterns, biophysical properties and ability to combine …

Gap junctions (GJ) provide direct intercellular communication. The structures underlying
these cell junctions are membrane-associated channels composed of six integral membrane …

Background Genetic factors are believed to be important in early-onset lone atrial fibrillation
(AF). The gene GJA5 encodes the gap-junction protein Cx40, which together with Cx43 is …

Connexin (Cx) expression and gap junctional intercellular communication (GJIC) are
involved in development and differentiation processes. Mediating exchanges between …