Pharmacological properties and molecular mechanisms of thymol: prospects for its therapeutic potential and pharmaceutical development

MF Nagoor Meeran, H Javed, H Al Taee… - Frontiers in …, 2017 - frontiersin.org
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline
monoterpene phenol. It is one of the most important dietary constituents in thyme species …

Nigella plants–Traditional uses, bioactive phytoconstituents, preclinical and clinical studies

B Salehi, C Quispe, M Imran, I Ul-Haq… - Frontiers in …, 2021 - frontiersin.org
Nigella is a small genus of the family Ranunculaceae, which includes some popular species
due to their culinary and medicinal properties, especially in Eastern Europe, Middle East …

Therapeutic significance of β-glucuronidase activity and its inhibitors: A review

P Awolade, N Cele, N Kerru, L Gummidi… - European journal of …, 2020 - Elsevier
The emergence of disease and dearth of effective pharmacological agents on most
therapeutic fronts, constitutes a major threat to global public health and man's existence …

Effects of Carvacrol, Thymol and essential oils containing such monoterpenes on wound healing: A systematic review

MF Costa, AO Durço, TK Rabelo… - Journal of pharmacy …, 2019 - academic.oup.com
Objectives The treatment of wounds accounts for a considerable fraction of health expenses
as well as serious socioeconomic problems. The use of natural substances stands out as a …

Thymol produces an antidepressant-like effect in a chronic unpredictable mild stress model of depression in mice

XY Deng, HY Li, JJ Chen, RP Li, R Qu, Q Fu… - Behavioural brain …, 2015 - Elsevier
Thymol, a bioactive monoterpene isolated from Thymus vulgaris, has displayed inspiring
neuroprotective properties. The present study was designed to evaluate the antidepressant …

Antioxidant and Anti-Inflammatory Effects of Thyme (Thymus vulgaris L.) Essential Oils Prepared at Different Plant Phenophases on Pseudomonas aeruginosa LPS …

E Pandur, G Micalizzi, L Mondello, A Horváth, K Sipos… - Antioxidants, 2022 - mdpi.com
Thyme (Thymus vulgaris L.) essential oil (TEO) is widely used as an alternative therapy
especially for infections of the upper respiratory tract. TEO possesses antiviral, antibacterial …

Effects of dietary organic acids and nature identical compounds on growth, immune parameters and gut microbiota of European sea bass

S Busti, B Rossi, E Volpe, S Ciulli, A Piva, F D'Amico… - Scientific reports, 2020 - nature.com
A 71-day study was conducted to explore the effect of increasing dietary levels (0, 250, 500,
1000 mg kg feed− 1; D0, D250, D500 and D1000, respectively) of a blend of …

[Retracted] Thyme Oil and Thymol Counter Doxorubicin‐Induced Hepatotoxicity via Modulation of Inflammation, Apoptosis, and Oxidative Stress

OM Ahmed, SR Galaly, MAMA Mostafa… - Oxidative Medicine …, 2022 - Wiley Online Library
Doxorubicin (DOX) is an effective anticancer agent with a wide spectrum of activities.
However, it has many adverse effects on various organs especially on the liver. Thymol, one …

[HTML][HTML] Monoterpenes modulating cytokines-A review

JSS Quintans, S Shanmugam, L Heimfarth… - Food and chemical …, 2019 - Elsevier
Inflammatory response can be driven by cytokine production and is a pivotal target in the
management of inflammatory diseases. Monoterpenes have shown that promising profile as …

Nootkatone attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats

MFN Meeran, S Azimullah, E Adeghate, S Ojha - Phytomedicine, 2021 - Elsevier
Background Myocardial infarction (MI) is a lethal manifestation of cardiovascular diseases.
Oxidative stress, inflammation, and subsequent cell death are known to play crucial roles in …