Background 35% of patients with pancreatic cancer have unresectable locally advanced
disease at diagnosis. Several studies have examined systemic chemotherapy with …

EMT and MET comprise the processes by which cells transit between epithelial and
mesenchymal states, and they play integral roles in both normal development and cancer …

In terms of mortality and survival, pancreatic cancer is one of the worst malignancies. Known
as a unique type of programmed cell death, cuprotosis contributes to tumor cell growth …

Gemcitabine is the first-line treatment for pancreatic adenocarcinoma, but is increasingly
used to treat breast, bladder, and non-small cell lung cancers. Despite such broad use …

Deaths from pancreatic ductal adenocarcinoma, also known as pancreatic cancer, rank
fourth among cancer-related deaths in the United States, yet the causes of pancreatic cancer …

Background: The BRCA1/2 proteins are involved in regulation of cellular proliferation by
DNA damage repair via homologous recombination. Therefore, BRCA1/2 mutation carriers …

Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United
States, with over 38000 deaths in 2013. The opportunity to detect pancreatic cancer while it …

Background The 8th edition of the AJCC staging system for pancreatic cancer incorporated
several significant changes. This study sought to evaluate this staging system and assess its …

Markers are needed to facilitate early detection of pancreatic ductal adenocarcinoma
(PDAC), which is often diagnosed too late for effective therapy. Starting with a PDAC cell …

The National Cancer Data Base (NCDB) is a nationwide oncology outcomes database that
currently collects information on approximately 70% of all new invasive cancer diagnoses in …