Cryptococcal meningitis

L Tugume, K Ssebambulidde, J Kasibante… - Nature Reviews …, 2023 - nature.com
Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Fungal infections in HIV/AIDS

AH Limper, A Adenis, T Le… - The Lancet Infectious …, 2017 - thelancet.com
Fungi are major contributors to the opportunistic infections that affect patients with HIV/AIDS.
Systemic infections are mainly with Pneumocystis jirovecii (pneumocystosis), Cryptococcus …

Single-dose liposomal amphotericin B treatment for cryptococcal meningitis

JN Jarvis, DS Lawrence, DB Meya… - … England Journal of …, 2022 - Mass Medical Soc
Background Cryptococcal meningitis is a leading cause of human immunodeficiency virus
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …

Adjunctive dexamethasone for tuberculous meningitis in HIV-positive adults

J Donovan, ND Bang, D Imran… - … England Journal of …, 2023 - Mass Medical Soc
Background Adjunctive glucocorticoids are widely used to treat human immunodeficiency
virus (HIV)–associated tuberculous meningitis despite limited data supporting their safety …

Antifungal combinations for treatment of cryptococcal meningitis in Africa

SF Molloy, C Kanyama, RS Heyderman… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …

Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy

PR Williamson, JN Jarvis, AA Panackal… - Nature Reviews …, 2017 - nature.com
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

Immunity to invasive fungal diseases

A Casadevall - Annual review of immunology, 2022 - annualreviews.org
Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

Cryptococcosis

AC Gushiken, KK Saharia, JW Baddley - Infectious Disease Clinics, 2021 - id.theclinics.com
Cryptococcosis is an infection of global significance, affecting both immunocompromised
and immunocompetent hosts. Traditionally, 2 main species of yeasts caused cryptococcosis …

Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM

CC Chang, TS Harrison, TA Bicanic… - The Lancet Infectious …, 2024 - thelancet.com
Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis,
particularly in its most lethal manifestation of cryptococcal meningitis, accounts for …

HIV-associated opportunistic CNS infections: pathophysiology, diagnosis and treatment

LN Bowen, B Smith, D Reich, M Quezado… - Nature Reviews …, 2016 - nature.com
Nearly 30 years after the advent of antiretroviral therapy (ART), CNS opportunistic infections
remain a major cause of morbidity and mortality in HIV-positive individuals. Unknown HIV …