The oxygen dissociation curve of blood in COVID-19–An update
An impressive effect of the infection with SARS-Co-19 is the impairment of oxygen uptake
due to lung injury. The reduced oxygen diffusion may potentially be counteracted by an …
due to lung injury. The reduced oxygen diffusion may potentially be counteracted by an …
The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications
PP Pagare, M McGinn, MS Ghatge… - Medicinal Research …, 2024 - Wiley Online Library
For the last two decades, the aromatic aldehyde 5‐hydroxymethyl‐furfural (5‐HMF) has
been the subject of several investigations for its pharmacologic potential. In 2004, the Safo …
been the subject of several investigations for its pharmacologic potential. In 2004, the Safo …
Comprehensive metabolomics and network pharmacology to explore the mechanism of 5-hydroxymethyl furfural in the treatment of blood deficiency syndrome
W Zhang, N Cui, F Su, Y Wang, B Yang… - Frontiers in …, 2022 - frontiersin.org
Radix Rehmanniae (RR, from Radix Rehmanniae (Gaertn.) DC.) is a natural medicine used
in traditional Chinese medicine (TCM) since ancient times for the treatment of blood …
in traditional Chinese medicine (TCM) since ancient times for the treatment of blood …
Influence of cigarettes on myocardial injury in healthy population after exposure to high altitude over 5000 m
S He, Q Zhang, F Wu, J Chen, S He, Z Ji, B Li… - Science of The Total …, 2023 - Elsevier
Background Myocardial injury (MI) is a severe complication once subjected to hypoxic
condition at high altitude. Little evidence exists about the association of cigarettes and MI at …
condition at high altitude. Little evidence exists about the association of cigarettes and MI at …
High-molecular-weight linear polymers improve microvascular perfusion after extracorporeal circulation
K Govender, C Walser… - Journal of Applied …, 2024 - journals.physiology.org
High-molecular-weight linear polymers (HMWLPs) have earned the name “drag-reducing
polymers” because of their ability to reduce drag in turbulent flows. Recently, these polymers …
polymers” because of their ability to reduce drag in turbulent flows. Recently, these polymers …
Solid-Phase Polymerization Using Anion-Exchange Resin Can Almost Completely Crosslink Hemoglobin to Prepare Hemoglobin-Based Oxygen Carriers
W Hui, W Mu, C Zhao, D Xue, Z Zhong… - International Journal …, 2023 - Taylor & Francis
Introduction A limitation of hemoglobin-based oxygen carriers (HBOCs) as oxygen
therapeutics is unpolymerized hemoglobin, which induces vasoconstriction leading to …
therapeutics is unpolymerized hemoglobin, which induces vasoconstriction leading to …
Extracorporeal circulation impairs microcirculation perfusion and organ function
K Govender, P Cabrales - Journal of Applied Physiology, 2022 - journals.physiology.org
Extracorporeal membrane oxygenation (ECMO) is a procedure used to aid respiratory
function in critical patients, involving extracorporeal circulation (ECC) of blood. There is a …
function in critical patients, involving extracorporeal circulation (ECC) of blood. There is a …
Safety profile of high molecular weight polymerized hemoglobins
CR Muller, AT Williams, CJ Munoz, AM Eaker… - …, 2021 - Wiley Online Library
Abstract Background Hemoglobin (Hb)‐based oxygen (O2) carriers (HBOCs) are being
developed as alternatives to red blood cells and blood when these products are …
developed as alternatives to red blood cells and blood when these products are …
Clinical outcomes of children and adolescents with sickle cell disease and COVID-19 infection: A year in review at a metropolitan tertiary pediatric hospital
OY Martin, DS Darbari, S Margulies, RS Nickel… - Frontiers in …, 2023 - frontiersin.org
Background COVID-19 was declared a global pandemic in March 2020. Early reports were
primarily in adults, and sickle cell disease (SCD) was classified as a risk factor for severe …
primarily in adults, and sickle cell disease (SCD) was classified as a risk factor for severe …
High‐throughput determination of oxygen dissociation curves in a microplate reader—A novel, quantitative approach
S Woyke, M Ströhle, H Brugger… - Physiological …, 2021 - Wiley Online Library
In vitro determination of the hemoglobin oxygen dissociation curve (ODC) requires highly
elaborate, specialized, and costly technical equipment. In addition, there is a lack of …
elaborate, specialized, and costly technical equipment. In addition, there is a lack of …