Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with
reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and …

The endothelial glycocalyx has a profound influence at the vascular wall on the transmission
of shear stress, on the maintenance of a selective permeability barrier and a low hydraulic …

The translation from numerous successful animal experiments on cardioprotection beyond
that by reperfusion to clinical practice has to date been disappointing. Animal experiments …

Myocardial infarct size is a major determinant of prognosis. Ischaemic preconditioning with
brief coronary occlusion and reperfusion before a sustained period of coronary occlusion …

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …

The mortality from acute myocardial infarction (AMI) remains significant, and the prevalence
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …

Coronary heart disease (CHD) is the leading cause of death and disability worldwide.
Despite current therapy, the morbidity and mortality for patients with CHD remains …

Current concepts of vascular permeability are largely still based on the Starling principle of
1896. Starling's contribution to understanding vascular fluid homeostasis comes from …