The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

Endothelial dysfunction is characterized by nitric oxide dysregulation and an altered redox
state. Oxidative stress and inflammatory markers prevail, thus promoting atherogenesis and …

Background Fatigue, exertion intolerance and post-exertional malaise are among the most
frequent symptoms of Post-COVID Syndrome (PCS), with a subset of patients fulfilling …

Ischaemic heart disease is a major cause of death and disability worldwide, while angina
represents its most common symptom. It is estimated that approximately 9 million patients in …

Heart rate plays a major role in myocardial ischemia. A high heart rate increases myocardial
performance and oxygen demand and reduces diastolic time. Ivabradine reduces heart rate …

Atherosclerosis‑induced cardiovascular diseases (CVDs) are accompanied by substantial
morbidity and mortality. The loss and injury of endothelial cells is the primary cause of …

Aim Heart rate (HR) is an important prognostic factor in patients affected by chronic heart
failure (CHF); ivabradine has been demonstrated to significantly reduce nonfatal myocardial …

Objective: Evaluating the vascular function in HIV-infected compared with HIV uninfected
with assessment of body composition, inflammation, and gut integrity markers. Design: A …

Abstract Stable angina pectoris affects 2–4% of the population in Western countries and
entails an annual risk of death and nonfatal myocardial infarction of 1–2% and 3 …

Introduction Ivabradine reduces heart rate (HR), episodes of angina, and nitrate
consumption, and increases exercise capacity in patients with chronic angina (CA). In this …