Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Developments in neuroradiological MRI analysis offer promise in enhancing objectivity and
consistency in dementia diagnosis through the use of quantitative volumetric reporting tools …

There is an increasing need of sharing harmonized data from large, cooperative studies as
this is essential to develop new diagnostic and prognostic biomarkers. In the field of multiple …

Background: Considerable spinal cord (SC) atrophy occurs in multiple sclerosis (MS). While
MRI-based techniques for SC cross-sectional area (CSA) quantification have improved over …

Several MRI measures have been developed in the last couple of decades, providing a
number of imaging biomarkers that can capture the complexity of the pathological processes …

Spinal cord imaging in multiple sclerosis (MS) plays a significant role in diagnosing and
tracking disease progression. The spinal cord is one of four key areas of the central nervous …

Objective We sought to characterize spinal cord atrophy along the entire spinal cord in the
major multiple sclerosis (MS) phenotypes, and evaluate its correlation with clinical disability …

Spinal cord (SC) atrophy obtained from structural magnetic resonance imaging has gained
relevance as an indicator of neurodegeneration in various neurological disorders. The …

Background We aimed to evaluate the implications for clinical trial design of the generalised
boundary-shift integral (GBSI) for spinal cord atrophy measurement. Methods We included …

Short MRI acquisition time, high signal-to-noise ratio, and high reliability are crucial for
image quality when scanning healthy volunteers and patients. Cross-sectional cervical cord …