Peroxisome proliferator-activated receptor (PPAR) β/δ belongs to the family of hormone and
lipid-activated nuclear receptors, which are involved in metabolism of long-chain fatty acids …

Peroxisome proliferator-activated receptors [PPARs; PPARα, PPARβ/δ (also known as
PPARδ), and PPARγ] widely recognized for their important role in glucose/lipid homeostasis …

Omega-9 monounsaturated fatty acids (ω-9 MUFAs) are a group of unsaturated fatty acids
with a unique double bond in the 9th position at the end of the methyl group terminal, having …

Elevated levels of cyclooxygenase‐2 (COX‐2) and prostaglandins (PGs) are involved in the
pathogenesis of Alzheimer's disease (AD), which is characterized by the accumulation of β …

In this review study, we focus on potential benefits of the transcription factor PPARδ and its
ligand erucic acid (EA) in management of neuroectodermal tumors and Parkinson's …

The transcription factor, PPARδ is involved in suppressing inflammation, stimulating
oligodendroglial biogenesis and myelination. Furthermore, activation of PPARδ directly …

Neuro-inflammation involves distinct alterations of microglial phenotypes, containing
nocuous pro-inflammatory M1-phenotype and neuroprotective anti-inflammatory M …

Brain injury has been proposed as the major cause of the poor outcomes associated with
intracerebral hemorrhage (ICH). Emerging evidence indicates that the nuclear receptor …

There is accumulating evidence that vitamin A (VA) deficiency contributes to the
pathogenesis and progression of Alzheimer's disease (AD). All-trans retinoic acid (ATRA), a …

Rationale: Alzheimer's disease (AD) is a progressive neurodegenerative disease
accompanied by neurotoxicity, excessive inflammation, and cognitive impairment. The …