Cancer overdiagnosis: a biological challenge and clinical dilemma
For cancer screening to be successful, it should primarily detect cancers with lethal potential
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …
Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer
Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor
prognosis can be attributed to both troublesome detections at the initial stage, which makes …
prognosis can be attributed to both troublesome detections at the initial stage, which makes …
Pancreatic cancer and cellular senescence: tumor microenvironment under the spotlight
Pancreatic ductal adenocarcinoma (PDAC) has one of the most dismal prognoses of all
cancers due to its late manifestation and resistance to current therapies. Accumulating …
cancers due to its late manifestation and resistance to current therapies. Accumulating …
Should we do EUS/FNA on patients with pancreatic cysts? The incremental diagnostic yield of EUS over CT/MRI for prediction of cystic neoplasms
Objectives To evaluate the performance characteristics of endoscopic ultrasonography
(EUS) compared with computed tomography (CT) and magnetic resonance imaging (MRI) …
(EUS) compared with computed tomography (CT) and magnetic resonance imaging (MRI) …
Polymeric micelles assisted combinatorial therapy: Is it new hope for pancreatic cancer?
U Rehman, MAS Abourehab, A Alexander… - European Polymer …, 2023 - Elsevier
Pancreatic cancer (PC) is a fatal disease that has a 5-year survival rate of less than 9%. It is
expected to rank second in cancer-related deaths across the United States by 2030. Out of …
expected to rank second in cancer-related deaths across the United States by 2030. Out of …
Pancreatic carcinogenesis
JBM Koorstra, SR Hustinx, GJA Offerhaus, A Maitra - Pancreatology, 2008 - karger.com
Pancreatic cancer is an almost universally lethal disease. Research over the last two
decades has shown that pancreatic cancer is fundamentally a genetic disease, caused by …
decades has shown that pancreatic cancer is fundamentally a genetic disease, caused by …
Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer
N Remmers, JM Anderson, EM Linde, DJ DiMaio… - Clinical Cancer …, 2013 - AACR
Purpose: Mucin expression is a common feature of most adenocarcinomas and features
prominently in current attempts to improve diagnosis and therapy for pancreatic cancer and …
prominently in current attempts to improve diagnosis and therapy for pancreatic cancer and …
Cystic lesions of the pancreas: a diagnostic and management dilemma
G Garcea, SL Ong, A Rajesh, CP Neal, CA Pollard… - Pancreatology, 2008 - Elsevier
Abstract Background/Aims: Due to enhanced imaging modalities, pancreatic cysts are being
increasingly detected, often as an incidental finding. They comprise a wide range of differing …
increasingly detected, often as an incidental finding. They comprise a wide range of differing …
Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine
Genetic studies have advanced our understanding of pancreatic cancer at a mechanistic
and translational level. Genetic concepts and tools are increasingly starting to be applied to …
and translational level. Genetic concepts and tools are increasingly starting to be applied to …
[HTML][HTML] Kras as a key oncogene and therapeutic target in pancreatic cancer
MA Collins, M Pasca Di Magliano - Frontiers in physiology, 2014 - frontiersin.org
Pancreatic cancer is one of the deadliest human malignancies and little progress has been
achieved in its treatment over the past decades. Advances in our understanding of the …
achieved in its treatment over the past decades. Advances in our understanding of the …