Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
[HTML][HTML] Lactobacillus and intestinal diseases: Mechanisms of action and clinical applications
R Huang, F Wu, Q Zhou, W Wei, J Yue, B Xiao… - Microbiological …, 2022 - Elsevier
The gut microbial ecosystem, which is a collection of the host-microbiota interactions and the
inter-species interplay among bacteria-dominated microbiota, has become a research …
inter-species interplay among bacteria-dominated microbiota, has become a research …
[HTML][HTML] NADPH oxidases and ROS signaling in the gastrointestinal tract
Reactive oxygen species (ROS), initially categorized as toxic by-products of aerobic
metabolism, have often been called a double-edged sword. ROS are considered …
metabolism, have often been called a double-edged sword. ROS are considered …
Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause?
A Rezaie, RD Parker, M Abdollahi - Digestive diseases and sciences, 2007 - Springer
Crohn's disease (CD) and ulcerative colitis (UC), known as inflammatory bowel disease
(IBD), are fairly common chronic inflammatory conditions of the gastrointestinal tract …
(IBD), are fairly common chronic inflammatory conditions of the gastrointestinal tract …
The blood-retina barrier: tight junctions and barrier modulation
M Campbell, P Humphries - Biology and regulation of blood-tissue …, 2013 - Springer
The blood-retina barrier (BRB) is composed of both an inner and an outer barrier. The outer
BRB refers to the barrier formed at the retinal pigment epithelial (RPE) cell layer and …
BRB refers to the barrier formed at the retinal pigment epithelial (RPE) cell layer and …
Occludin: structure, function and regulation
GJ Feldman, JM Mullin, MP Ryan - Advanced drug delivery reviews, 2005 - Elsevier
Epithelial and/or endothelial barriers play a critical role in animal, including human, life
forms. The tight junction (TJ) is an essential component of these barriers. Occludin is a major …
forms. The tight junction (TJ) is an essential component of these barriers. Occludin is a major …
Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC-and MAP kinase-dependent mechanism
Probiotics promote intestinal epithelial integrity and reduce infection and diarrhea. We
evaluated the effect of Lactobacillus rhamnosus GG-produced soluble proteins (p40 and …
evaluated the effect of Lactobacillus rhamnosus GG-produced soluble proteins (p40 and …
Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury
The primary function of neutrophils in host defense is to contain and eradicate invading
microbial pathogens. This is achieved through a series of swift and highly coordinated …
microbial pathogens. This is achieved through a series of swift and highly coordinated …
Tyrosine phosphorylation and dissociation of occludin–ZO-1 and E-cadherin–β-catenin complexes from the cytoskeleton by oxidative stress
RK Rao, S Basuroy, VU Rao, KJ Karnaky Jr… - Biochemical …, 2002 - portlandpress.com
The oxidative-stress-induced alteration in paracellular junctional complexes was analysed
in Caco-2 cell monolayer. Oxidative stress induced a rapid increase in tyrosine …
in Caco-2 cell monolayer. Oxidative stress induced a rapid increase in tyrosine …
Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic …
BACKGROUND/AIMS: Not all alcoholics develop liver disease (ALD). Thus, excessive
ethanol consumption is necessary, but not sufficient, to induce alcoholic steatohepatitis …
ethanol consumption is necessary, but not sufficient, to induce alcoholic steatohepatitis …