Green synthesis of biologically active heterocycles of medicinal importance: A review
Heterocyclic moieties are basic skeletons for 80% of commercial medicines according to the
US retail market in 2014–2015, yet many actual synthetic methods are not sustainable …
US retail market in 2014–2015, yet many actual synthetic methods are not sustainable …
An overview of metal-free synthetic routes to isoxazoles: the privileged scaffold
In the field of drug discovery, isoxazole is a five-membered heterocyclic moiety commonly
found in many commercially available drugs. In view of their enormous significance, it is …
found in many commercially available drugs. In view of their enormous significance, it is …
In-silico molecular modelling, MM/GBSA binding free energy and molecular dynamics simulation study of novel pyrido fused imidazo[4,5-c]quinolines as potential …
With an alarming increase in the number of cancer patients and a variety of tumors, it is high
time for intensive investigation on more efficient and potent anti-tumor agents. Though …
time for intensive investigation on more efficient and potent anti-tumor agents. Though …
2-Aminopyridine–an unsung hero in drug discovery
2-Aminopyridine is a simple, low molecular weight and perfectly functionalised moiety
known for the synthesis of diverse biological molecules. Many pharmaceutical companies …
known for the synthesis of diverse biological molecules. Many pharmaceutical companies …
Photophysical evaluation on the electronic properties of synthesized biologically significant pyrido fused imidazo [4, 5-c] quinolines
A single pot microwave assisted method was employed to synthesize a series of novel
pyrido fused imidazo [4, 5-c] quinolines. The electronic properties of these derivatives were …
pyrido fused imidazo [4, 5-c] quinolines. The electronic properties of these derivatives were …
Novel Neuroprotective 5, 6-Dihydropyrido [2', 1': 2, 3] imidazo [4, 5-c] quinoline Derivatives Acting Through Cholinesterase Inhibition and CB2 Signaling Modulation
S Jena, G Gonzalez, D Vítek, M Kvasnicová… - European Journal of …, 2024 - Elsevier
Abstract A novel group of 5, 6-dihydropyrido [2', 1': 2, 3] imidazo [4, 5-c] quinolines was
prepared via a microwave assisted one-pot telescopic approach. The synthetic sequence …
prepared via a microwave assisted one-pot telescopic approach. The synthetic sequence …
Microwave-assisted Cu (i)-catalyzed one-pot tandem synthesis of pyridoimidazole-fused quinolines as new antimycobacterial agents: DFT and ESI-HRMS study
In this study, an improved microwave irradiation protocol was developed for synthesizing
pyrido [2′, 1′: 2, 3] imidazo [4, 5-c] quinoline from 2-(2-bromophenyl) imidazo [1, 2-a] …
pyrido [2′, 1′: 2, 3] imidazo [4, 5-c] quinoline from 2-(2-bromophenyl) imidazo [1, 2-a] …
Recent Advances in the Synthesis of Fused‐Cyclic Quinolines
SA Darbandizadeh, S Balalaie - Asian Journal of Organic …, 2024 - Wiley Online Library
Fused quinolines have gained substantial attention due to their significant biological and
wide‐spectrum synthetic applications. This review supplies an encyclopedic document …
wide‐spectrum synthetic applications. This review supplies an encyclopedic document …
Molybdenum‐Catalyzed One‐Pot Multi‐Step Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols
S Gómez‐Gil, N Cases… - European Journal of …, 2024 - Wiley Online Library
We report the efficient, sustainable one‐pot synthesis of a wide variety of N‐
polyheterocycles, such as imidazo‐quinolines and quinoxalines, and furoquinolines, from …
polyheterocycles, such as imidazo‐quinolines and quinoxalines, and furoquinolines, from …
Six-membered ring systems: pyridines and benzo derivatives
JC Badenock - Progress in Heterocyclic Chemistry, 2023 - Elsevier
The class of pyridines and their benzo derivatives maintain prominence in the synthetic
literature due to their versatility and chemical and biological properties. These scaffolds …
literature due to their versatility and chemical and biological properties. These scaffolds …