Antifungal therapy: new advances in the understanding and treatment of mycosis

L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Yeast surface display system: strategies for improvement and biotechnological applications

KV Teymennet-Ramírez, F Martínez-Morales… - … in Bioengineering and …, 2022 - frontiersin.org
Yeast surface display (YSD) is a “whole-cell” platform used for the heterologous expression
of proteins immobilized on the yeast's cell surface. YSD combines the advantages …

Applications of yeast surface display for protein engineering

GM Cherf, JR Cochran - Yeast Surface Display: Methods, Protocols, and …, 2015 - Springer
The method of displaying recombinant proteins on the surface of Saccharomyces cerevisiae
via genetic fusion to an abundant cell wall protein, a technology known as yeast surface …

Yeast as carrier for drug delivery and vaccine construction

Y Tan, L Chen, K Li, B Lou, Y Liu, Z Liu - Journal of Controlled Release, 2022 - Elsevier
Yeast has been employed as an effective derived drug carrier as a unicellular
microorganism. Many research works have been devoted to the encapsulation of nucleic …

Candidiasis: A fungal infection-current challenges and progress in prevention and treatment

U Hani, HG Shivakumar, R Vaghela… - … Current Drug Targets …, 2015 - ingentaconnect.com
Despite therapeutic advances candidiasis remains a common fungal infection most
frequently caused by C. albicans and may occur as vulvovaginal candidiasis or thrush, a …

The Role of B-Cells and Antibodies against Candida Vaccine Antigens in Invasive Candidiasis

M Shukla, P Chandley, S Rohatgi - Vaccines, 2021 - mdpi.com
Systemic candidiasis is an invasive fungal infection caused by members of the genus
Candida. The recent emergence of antifungal drug resistance and increased incidences of …

Aspartic Proteases and Major Cell Wall Components in Candida albicans Trigger the Release of Neutrophil Extracellular Traps

M Zawrotniak, O Bochenska… - Frontiers in cellular …, 2017 - frontiersin.org
Neutrophils use different mechanisms to cope with pathogens that invade the host organism.
The most intriguing of these responses is a release of neutrophil extracellular traps (NETs) …

Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules

I Legastelois, S Buffin, I Peubez, C Mignon… - Human vaccines & …, 2017 - Taylor & Francis
The increasing demand for recombinant vaccine antigens or immunotherapeutic molecules
calls into question the universality of current protein expression systems. Vaccine production …

Yeast oral vaccines against infectious diseases

N Austriaco - Frontiers in Microbiology, 2023 - frontiersin.org
Vaccines that are delivered orally have several advantages over their counterparts that are
administered via injection. Despite the advantages of oral delivery, however, approved oral …

Preliminary study of an oral vaccine against infectious hematopoietic necrosis virus using improved yeast surface display technology

JZ Zhao, LM Xu, M Liu, YS Cao, SE LaPatra, JS Yin… - Molecular …, 2017 - Elsevier
Infectious hematopoietic necrosis virus (IHNV) is a common pathogen that causes severe
disease in the salmonid aquaculture industry. Because oral vaccines induce more efficient …