Molecular diagnostics in cancer should provide the highest specificity and sensitivity in
classification, prognostic stratification and early detection. miRNAs could contribute to hitting …

It is well established that microRNAs (miRNAs) induce mRNA degradation by binding to 3′
untranslated regions (UTRs). The functionality of sites in the coding domain sequence …

Hepatocyte nuclear factor 4α (HNF4α) is essential for liver development and hepatocyte
function. Here, we show that transient inhibition of HNF4α initiates hepatocellular …

Most of what is presently known about how miRNAs regulate gene expression comes from
studies that characterized the regulatory effect of miRNA binding sites located in the 3 …

Small non-coding microRNAs (miRNAs) are epigenetic regulators that target specific cellular
mRNA to modulate gene expression patterns and cellular signaling pathways. miRNAs are …

Specific microRNAs have emerged as key players in disease biology by playing crucial role
in disease development and progression. This review draws attention to one such …

The diagnosis of cancer has undergone major changes in the last 40 years. Once based
purely on morphology, diagnosis has come to incorporate immunological, cytogenetic and …

The complex microRNA (miRNA) network plays an important role in the regulation of cellular
processes such as development, differentiation, and apoptosis. Recently, the presence of …

Abstract The Epstein–Barr virus (EBV) is an oncogenic human Herpes virus found in∼ 15%
of diffuse large B-cell lymphoma (DLBCL). EBV encodes miRNAs and induces changes in …

MAGIA (miRNA and genes integrated analysis) is a novel web tool for the integrative
analysis of target predictions, miRNA and gene expression data. MAGIA is divided into two …