Antioxidant Activity, Molecular Docking and Quantum Studies of New Bis‐Schiff Bases Based on Benzyl Phenyl Ketone Moiety

R Ahmad, A Alam, M Khan, T Ali, AA Elhenawy… - …, 2023 - Wiley Online Library
In the current research work novel bis‐Schiff base products of benzyl phenyl ketone nucleus
were synthesized via two step reactions in excellent yields. Using FTIR, EI‐MS and 1H‐NMR …

Antibacterial, antiurease, and antioxidant activities of some arylidene barbiturates

BB Sokmen, S Ugras, HY Sarikaya, HI Ugras… - Applied biochemistry …, 2013 - Springer
Some series of arylidene barbiturates and thiobarbiturates were evaluated for their
antibacterial, antioxidant, and urease inhibition activities. The arylidene barbiturates and …

Discovery of 5-(3, 4-dihydroxybenzylidene)-1, 3-dimethylpyrimidine-2, 4, 6 (1H, 3H, 5H)-trione as a novel and effective cardioprotective agent via dual anti …

YY Shi, B Wei, J Zhou, ZL Yin, F Zhao, YJ Peng… - European Journal of …, 2022 - Elsevier
Myocardial ischemia/reperfusion (MI/R) injury is still the huge unmet medical need without
effective therapy in clinic. It is critical to develop pharmacological intervention to scavenge …

Synthesis and structure–activity relationship of thiobarbituric acid derivatives as potent inhibitors of urease

KM Khan, F Rahim, A Khan, M Shabeer… - Bioorganic & Medicinal …, 2014 - Elsevier
A series of thiobarbituric acid derivatives 1–27 were synthesized and evaluated for their
urease inhibitory potential. Exciting results were obtained from the screening of these …

Synthesis, evaluation of antioxidant activity and crystal structure of 2, 4-dimethylbenzoylhydrazones

M Taha, NH Ismail, W Jamil, S Yousuf, FM Jaafar, MI Ali… - Molecules, 2013 - mdpi.com
2, 4-Dimethylbenzoylhydrazones 1–30 were synthesized by condensation reactions of 2, 4-
dimethylbenzoylhydrazide with various aromatic aldehydes and characterized. The …

[HTML][HTML] Synthesis of magnetized inorganic–Phycocyanin nanohybrid [CoFe2O4-SiO2@ PC-Cu (II)] as an environmentally friendly nanocomposite catalyst for the …

E Mashhadi, J Safaei-Ghomi, A Iraji - Environmental Technology & …, 2024 - Elsevier
The increasing need for sustainable and environmentally friendly materials has directed
scientific attention toward using biodegradable resources. In this study, we developed a …

High diastereoselective synthesis of spiro-barbituratechromans via domino oxa-Michael/1, 6-addition reactions of ortho-hydroxyphenylsubstituted para-quinone …

M Huo, J Zhou, L Bai, Q Xu, Z Zhou, H Zhou, G Liang - Tetrahedron, 2019 - Elsevier
A novel Et 3 N-catalyzed domino oxa-Michael/1, 6-addition reaction of ortho-
hydroxyphenylsubstituted p-QMs with barbiturate-based olefins is achieved under mild …

Synthesis of 2-(2-methoxyphenyl)-5-phenyl-1, 3, 4-oxadiazole derivatives and evaluation of their antiglycation potential

M Taha, NH Ismail, W Jamil, S Imran, F Rahim… - Medicinal Chemistry …, 2016 - Springer
In the search of potent antidiabetic drug, we synthesized 1–25 2-(2-methoxyphenyl)-5-
phenyl-1, 3, 4-oxadiazole derivatives. First, we synthesized 2-methoxybenzohydrazide from …

Synthesis, molecular modeling and biological evaluation of 5-arylidene-N, N-diethylthiobarbiturates as potential α-glucosidase inhibitors

M Khan, S Khan, A Ul Mulk, A Ur Rahman… - Medicinal …, 2019 - ingentaconnect.com
Background: Barbituric acid derivatives are a versatile group of compounds which are
identified as potential pharmacophores for the treatment of anxiety, epilepsy and other …

Gelation-driven selection in dynamic covalent C [double bond, length as m-dash] C/C [double bond, length as m-dash] N exchange

C Liang, S Kulchat, S Jiang, JM Lehn - Chemical Science, 2017 - pubs.rsc.org
Knoevenagel barbiturate derivatives bearing long alkyl chains were proven to form
organogels in suitable solvents based on supramolecular interactions. Their reaction with …