Background Life-threatening haemorrhage accounts for 40% mortality in trauma patients
worldwide. After bleeding control is achieved, circulating volume must be restored. Early in …

Background After a person has been injured, prehospital administration of plasma in
addition to the initiation of standard resuscitation procedures in the prehospital environment …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Importance Both military and civilian clinical practice guidelines include early plasma
transfusion to achieve a plasma to red cell ratio approaching 1: 1 to 1: 2. However, it was not …

Trauma resuscitation should focus on early goal-directed therapy with use of viscoelastic
haemostatic assays while initially applying a ratio 1: 1: 1 driven transfusion therapy (with red …

Following advances in blood typing and storage, whole blood transfusion became available
for the treatment of casualties during World War I. While substantially utilized during World …

The primary aim of this systematic review is to describe the effects of prehospital transfusion
of red blood cells (PHTRBC) on patient outcomes. Damage control resuscitation attempts to …

Introduction Catastrophic haemorrhage is recognised as the leading cause of preventable
death in trauma and is also prevalent in medical and other surgical aetiology. Prehospital …

Objectives The primary aim of this scoping review is to describe the current use of pre‐
hospital transfusion of red blood cells (PHTRBC) and to evaluate criteria used to initiate …

Exsanguination is the leading cause of death in severely injured patients; nevertheless,
prehospital blood transfusion (PHT) remains a controversial topic. Here, we review the pros …