[HTML][HTML] The peripheral immune system and traumatic brain injury: Insight into the role of T-helper cells
W Bao, Y Lin, Z Chen - International Journal of Medical Sciences, 2021 - ncbi.nlm.nih.gov
Emerging evidence suggests that immune-inflammatory processes are key elements in the
physiopathological events associated with traumatic brain injury (TBI). TBI is followed by T …
physiopathological events associated with traumatic brain injury (TBI). TBI is followed by T …
Monocyte mobilisation, microbiota & mental illness
The gastrointestinal microbiome has emerged as a key player in regulating brain and
behaviour. This has led to the strategy of targeting the gut microbiota to ameliorate disorders …
behaviour. This has led to the strategy of targeting the gut microbiota to ameliorate disorders …
Impaired glymphatic function in the early stages of disease in a TDP-43 mouse model of amyotrophic lateral sclerosis
Background Multiple lines of evidence suggest possible impairment of the glymphatic
system in amyotrophic lateral sclerosis (ALS). To investigate this, we used in vivo magnetic …
system in amyotrophic lateral sclerosis (ALS). To investigate this, we used in vivo magnetic …
[HTML][HTML] Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: novel insights using a clinically relevant rat model
A history of mild traumatic brain injury (mTBI) is linked to a number of chronic neurological
conditions, however there is still much unknown about the underlying mechanisms. To …
conditions, however there is still much unknown about the underlying mechanisms. To …
Synchronizing our clocks as we age: the influence of the brain-gut-immune axis on the sleep-wake cycle across the lifespan
M Sgro, ZN Kodila, RD Brady, AC Reichelt… - Sleep, 2022 - academic.oup.com
The microbes that colonize the small and large intestines, known as the gut microbiome,
play an integral role in optimal brain development and function. The gut microbiome is a vital …
play an integral role in optimal brain development and function. The gut microbiome is a vital …
Treatment with the vascular endothelial growth factor-A antibody, bevacizumab, has sex-specific effects in a rat model of mild traumatic brain injury
M Sun, TL Baker, CT Wilson, RD Brady… - Journal of Cerebral …, 2024 - journals.sagepub.com
Mild traumatic brain injury (mTBI) involves damage to the cerebrovascular system. Vascular
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …
Roadmap for advancing pre-clinical science in traumatic brain injury
Pre-clinical models of disease have long played important roles in the advancement of new
treatments. However, in traumatic brain injury (TBI), despite the availability of numerous …
treatments. However, in traumatic brain injury (TBI), despite the availability of numerous …
The need to incorporate aged animals into the preclinical modeling of neurological conditions
M Sun, SJ McDonald, RD Brady… - Neuroscience & …, 2020 - Elsevier
Neurological conditions such as traumatic brain injury, stroke, Parkinson's disease, epilepsy,
multiple sclerosis, and Alzheimer's disease are serious clinical problems that affect millions …
multiple sclerosis, and Alzheimer's disease are serious clinical problems that affect millions …
[HTML][HTML] Function of glia in aging and the brain diseases
SL Valles, A Iradi, M Aldasoro, JM Vila… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Microglia cells during aging, neurodegeneration and neuroinflammation show different
morphological and transcriptional profiles (related to axonal direction and cell adhesion) …
morphological and transcriptional profiles (related to axonal direction and cell adhesion) …
Traumatic brain injury: an age-dependent view of post-traumatic neuroinflammation and its treatment
C Delage, T Taib, C Mamma, D Lerouet, VC Besson - Pharmaceutics, 2021 - mdpi.com
Traumatic brain injury (TBI) is a leading cause of death and disability all over the world. TBI
leads to (1) an inflammatory response,(2) white matter injuries and (3) neurodegenerative …
leads to (1) an inflammatory response,(2) white matter injuries and (3) neurodegenerative …