Zinc (Zn) nutritional importance has been known for a long time, but in the last decades its
importance in immune modulation has arisen. This review aims at describing the …

The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology.
The recent development of powerful tools, including zinc-sensitive fluorescent probes …

Two families of zinc (Zn2+) transporters are involved in zinc homeostasis in the body, SLC30
(ZnT, zinc transporter) and SLC39 (ZIP, Zinc (Zn2+)–Iron (Fe2+) Permease). The two zinc …

Abstract The Cation Diffusion Facilitators (CDFs) form a family of membrane-bound proteins
capable of transporting zinc and other heavy metal ions. Involved in metal …

Zinc, which is involved in the structure of all enzyme classes, is a micro nutrient element and
necessary for growth and development. The ability of zinc to function without causing toxic …

Evidence from both preclinical and clinical studies suggest the importance of zinc
homeostasis in seizures/epilepsy. Undoubtedly, zinc, via modulation of a variety of targets, is …

Zinc is required for the regulation of proliferation, metabolism, and cell signaling. It is an
intracellular second messenger, and the cellular level of ionic, mobile zinc is strictly …

Zinc is one of the most important metal nutrients for species from all kingdoms, being a key
structural or catalytic component of hundreds of enzymes, crucial for the survival of both …

Introduction Zinc homeostasis is regulated by SLC39A/ZIP, SLC30A/ZnT, and
metallothionein (MT) families in human cells. Zinc dyshomeostasis may affect or be affected …

Abstract ZnT-1 is a Cation Diffusion Facilitator (CDF) family protein, and is present
throughout the phylogenetic tree from bacteria to humans. Since its original cloning in 1995 …