Organophosphate esters (OPEs) are a group of pollutants that are widely detected in the
environment at high concentrations. They can adversely affect human health through …

The cutaneous absorption parameters of xenobiotics are crucial for the development of
drugs and cosmetics, as well as for assessing environmental and occupational chemical …

Transdermal drug delivery is a key technology for administering drugs. However, most
devices are “one-size-fits-all”, even though drug diffusion through the skin varies …

Transdermal drug delivery systems are a key technology to administer drugs with a high first-
pass effect in a non-invasive and controlled way. Physics-based modeling and simulation …

The skin acts as a physical barrier to protect the body from the external physical and
chemical environment. When skin is infected, the outer epidermal barrier is compromised …

Many questions concerning the biophysical and physiological properties of skin are still
open. Skin aging, permeability, dermal absorption, hydration, and drug transdermal delivery …

In vivo skin permeation studies are considered gold standard but are difficult to perform and
evaluate due to ethical issues and complexity of process involved. In recent past, a useful …

Background: A great deal of In Silico estimation methods were proposed for skin
concentration and permeation of drugs by many researchers including us. The aim of the …

This thesis presents a significant advance in selection of drug candidates for transdermal
drug delivery. The methodology uses molecular dynamics simulations to understand the …

Many questions concerning the biophysical and physiological properties of skin are still
open. Skin aging, permeability, dermal absorption, hydration and drug transdermal delivery …