Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …

This guideline presents recommendations for the management of patients with hereditary
gastrointestinal cancer syndromes. The initial assessment is the collection of a family history …

Context.—Familial adenomatous polyposis (FAP) is a rare genetic disorder with autosomal
dominant inheritance, defined by numerous adenomatous polyps, which inevitably progress …

Differentiated thyroid cancer (DTC) is a rare malignant disease, although its incidence has
increased over the last few decades. It derives from follicular thyroid cells. Generally …

The regulation of cell growth and survival can be subverted by a variety of genetic defects
that alter transcriptional programs normally responsible for controlling cell number. High …

This volume covers tumors of the pituary, the thyroid and parathyroid, the adrenal gland, the
endocrine pancreas, and inherited tumor syndromes. Each entity is extensively discussed …

Familial adenomatous polyposis (FAP) is an autosomal-dominant colorectal cancer
syndrome, caused by a germline mutation in the adenomatous polyposis coli (APC) gene …

Cancer development depends on the aberrant activation of signal transduction pathways
that control cell growth and survival and play important roles in normal embryonic …

The past two decades have brought many important advances in our understanding of the
hereditary susceptibility to cancer. Approximately 5–10% of all cancers are inherited, the …

Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited disorder, which
results from a germ line mutation in the APC (adenomatous polyposis coli) gene. FAP is …