The pathobiology of atherosclerotic disease requires further elucidation to discover new
approaches to address its high morbidity and mortality. To date, over 17 million …

Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …

Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Atherosclerosis is a chronic progressive inflammatory process that can eventually lead to
cardiovascular disease (CVD). Despite available treatment, the prevalence of …

Objective: Vascular calcification is common among aging populations and mediated by
vascular smooth muscle cells (VSMCs). The endoplasmic reticulum (ER) is involved in …

Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening condition characterized
by medial layer degeneration of the thoracic aorta. A thorough understanding of the …

Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

Extracellular vesicles (EVs) are cornerstones of intercellular communication with exciting
fundamental, clinical, and more broadly biotechnological applications. However, variability …

Abdominal aortic aneurysm (AAA) is a common vascular disease associated with significant
phenotypic alterations in vascular smooth muscle cells (VSMCs). Gasdermin D (GSDMD) is …