Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures

P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …

An updated review on bluetongue virus: epidemiology, pathobiology, and advances in diagnosis and control with special reference to India

M Saminathan, KP Singh, JH Khorajiya… - Veterinary …, 2020 - Taylor & Francis
Bluetongue (BT) is an economically important, non-contagious viral disease of domestic and
wild ruminants. BT is caused by BT virus (BTV) and it belongs to the genus Orbivirus and …

A method for rapid production of heteromultimeric protein complexes in plants: assembly of protective bluetongue virus‐like particles

EC Thuenemann, AE Meyers, J Verwey… - Plant biotechnology …, 2013 - Wiley Online Library
Plant expression systems based on nonreplicating virus‐based vectors can be used for the
simultaneous expression of multiple genes within the same cell. They therefore have great …

Prospects of next-generation vaccines for bluetongue

PA Van Rijn - Frontiers in Veterinary Science, 2019 - frontiersin.org
Bluetongue (BT) is a haemorrhagic disease of wild and domestic ruminants with a huge
economic worldwide impact on livestock. The disease is caused by BT-virus transmitted by …

Follicular dendritic cell disruption as a novel mechanism of virus-induced immunosuppression

E Melzi, M Caporale, M Rocchi… - Proceedings of the …, 2016 - National Acad Sciences
Arboviruses cause acute diseases that increasingly affect global health. We used
bluetongue virus (BTV) and its natural sheep host to reveal a previously uncharacterized …

Vaccines for prevention of bluetongue and epizootic hemorrhagic disease in livestock: A North American perspective

DS McVey, NJ MacLachlan - Vector-Borne and Zoonotic Diseases, 2015 - liebertpub.com
Bluetongue (BT) and epizootic hemorrhagic disease (EHD) are noncontagious, insect-
transmitted diseases of domestic and wild ruminants caused by related but distinct viruses …

Current and next-generation bluetongue vaccines: Requirements, strategies, and prospects for different field situations

F Feenstra, PA Van Rijn - Critical reviews in microbiology, 2017 - Taylor & Francis
Bluetongue virus (BTV) causes the hemorrhagic disease bluetongue (BT) in ruminants. The
best way to control outbreaks is vaccination. Currently, conventionally modified-live and …

[HTML][HTML] Recombinant vaccines against bluetongue virus

E Calvo-Pinilla, J Castillo-Olivares, T Jabbar, J Ortego… - Virus Research, 2014 - Elsevier
Bluetongue (BT) is a hemorrhagic disease of ruminants caused by bluetongue virus (BTV),
the prototype member of the genus Orbivirus within the family Reoviridae and is transmitted …

Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens

SY Lin, YC Chung, YC Hu - Expert review of vaccines, 2014 - Taylor & Francis
After three decades of development, the baculovirus/insect cell expression system is now
recognized as a powerful platform for recombinant protein production. With a number of …

Nanoparticle-and microparticle-based vaccines against orbiviruses of veterinary importance

L Jiménez-Cabello, S Utrilla-Trigo, N Barreiro-Piñeiro… - Vaccines, 2022 - mdpi.com
Bluetongue virus (BTV) and African horse sickness virus (AHSV) are widespread
arboviruses that cause important economic losses in the livestock and equine industries …