Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor
in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved …

Objective Intermittent fasting (IF) is a term used to describe a variety of eating patterns in
which no or few calories are consumed for time periods that can range from 12 hours to …

Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

Our understanding of the process of autophagy and its role in health and diseases has
grown remarkably in the last two decades. Early work established autophagy as a general …

Moderately trained male subjects (mean age 25 years; range 19–33 years) completed an 8‐
week exercise training intervention consisting of continuous moderate cycling at 157±20 W …

Background and Purpose Increasing evidence suggests systemic inflammation‐caused
skeletal muscle atrophy as a major clinical feature of cachexia. Triptolide obtained from …

Chronic inflammation is a hallmark of cancer cachexia in both patients and preclinical
models. Cachexia is prevalent in roughly 80% of cancer patients and accounts for up to 20 …

The aim of the present study was to examine the role of PGC-1α in intensity dependent
exercise and exercise training-induced metabolic adaptations in mouse skeletal muscle …

The quality control of skeletal muscle is a continuous requirement throughout the lifetime,
although its functions and quality present as a declining trend during aging process …

High incidences of morbidity and mortality associated with age-related diseases among the
elderly population are a socio-economic challenge. Aging is an irreversible and inevitable …