During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …

Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

Purpose To obtain whole lung morphometry measurements from 129Xe in a single breath‐
hold with 3D multiple b‐value 129Xe diffusion‐weighted MRI (DW‐MRI) with an empirically …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Nonuniform disruption of lung architecture is usually assessed by CT, which carries potential
radiation risk. Here we report our use of a three‐dimensional ultrashort echo time MR …

Mechanical ventilation is a life-saving therapy in patients with acute respiratory distress
syndrome (ARDS). However, mechanical ventilation itself causes severe co-morbidities in …

Despite decades of research into the mechanisms of lung inflation and deflation, there is
little consensus about whether lung inflation occurs due to the recruitment of new alveoli or …

Purpose Chronic obstructive pulmonary disease (COPD) is an irreversible lung disease
characterized by small‐airway obstruction and alveolar‐airspace destruction …

Purpose To quantitatively characterize early emphysematous changes in the lung
microstructure of current and former smokers with noninvasive helium 3 (3He) lung …

The introduction of hyperpolarized gases (3He and 129Xe) has opened the door to
applications for which gaseous agents are uniquely suited—lung MRI. One of the pulmonary …