Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes
A Sanchez, P Ortega, R Sakhtemani… - Nature …, 2024 - nature.com
Antiviral DNA cytosine deaminases APOBEC3A and APOBEC3B are major sources of
mutations in cancer by catalyzing cytosine-to-uracil deamination. APOBEC3A preferentially …
mutations in cancer by catalyzing cytosine-to-uracil deamination. APOBEC3A preferentially …
[HTML][HTML] Single-molecule insights into repetitive helicases
YM Zhang, B Li, WQ Wu - Journal of Biological Chemistry, 2024 - Elsevier
Helicases are ubiquitous motors involved in almost all aspects of nucleic acid metabolism;
therefore, revealing their unwinding behaviors and mechanisms is fundamentally and …
therefore, revealing their unwinding behaviors and mechanisms is fundamentally and …