CRISPR/Cas-powered amplification-free detection of nucleic acids: current state of the art, challenges, and futuristic perspectives

Y Li, Y Liu, X Tang, J Qiao, J Kou, S Man, L Zhu… - ACS …, 2023 - ACS Publications
CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …

Chemotactic Micro/Nanomotors for Biomedical Applications

X Xia, Y Li, X Xiao, Z Zhang, C Mao, T Li, M Wan - Small, 2024 - Wiley Online Library
In nature, many organisms respond chemotactically to external chemical stimuli in order to
extract nutrients or avoid danger. Inspired by this natural chemotaxis, micro/nanomotors with …

[HTML][HTML] Emerging microfluidic technologies for sperm sorting

J Huang, H Chen, N Li, Y Zhao - Engineered Regeneration, 2023 - Elsevier
Sorting high-quality sperm with intact DNA, normal morphology, and active motility is crucial
for clinically assisted reproductive technology, which influences the success of treatment …

Qualified sperm selection based on the rheotaxis and thigmotaxis in a microfluidic system

N Ahmadkhani, M Saadatmand, S Kazemnejad… - Biomedical Engineering …, 2023 - Springer
Microfluidic systems with the ability to mimic the female reproductive tract (FRT) and sperm
features have emerged as promising methods to separate sperm with higher quality for the …

CRISPR: The frontier technology of next-generation RNA detection

L Zhou, W Xu, J Kong, X Zhang - Biochemical Engineering Journal, 2024 - Elsevier
Rapid and accurate molecular diagnostics are crucial for disease diagnosis and precision
medicine. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and …

Microfluidic thermotaxic selection of highly motile sperm and in vitro fertilization

S Chen, J Chen, Z Qin, J Wang, Y Wang, R Liu… - Bio-Design and …, 2024 - Springer
The selection of the most motile and functionally competent sperm is an essential basis for in
vitro fertilization (IVF) and normal embryonic development. Widely adopted clinical …

Automatic high-throughput and non-invasive selection of sperm at the biochemical level

Y Mu, X Zhou, L Li, X Liu, X Wen, L Zhang, B Yan… - Med, 2024 - cell.com
Background Sperm selection, a key step in assisted reproductive technology (ART), has
long been restrained at the preliminary physical level (morphology or motility); however …