The twilight of the immune system: The impact of immunosenescence in aging
Cellular senescence is a critical part of human anti-tumor defence; however, the
accumulation of senescent cells with age underpins a wide range of pathologies. Senescent …
accumulation of senescent cells with age underpins a wide range of pathologies. Senescent …
Potential role of diabetes mellitus-associated T cell senescence in epithelial ovarian cancer omental metastasis
R Broadway, NM Patel, LE Hillier, A El-Briri… - Life, 2021 - mdpi.com
Epithelial ovarian cancer (EOC) is one of the most common causes of cancer-related deaths
among women and is associated with age and age-related diseases. With increasing …
among women and is associated with age and age-related diseases. With increasing …
Increased death and exhaustion of CD69high T cells and NK cells are associated with PD-1 antibody application in the in vitro co-culture system
Y Wang, Z Sun, X Du, Q Yu, C Sun, J Huang, L Wang - PeerJ, 2023 - peerj.com
Background The application of PD-1 monoclonal antibody (mAb) helps to treat non-small
cell lung cancer, but acquired resistance has emerged in clinical practice. We tested the …
cell lung cancer, but acquired resistance has emerged in clinical practice. We tested the …
Unraveling the potential of senescence-related genes in guiding clinical therapy of lung adenocarcinoma patients
C Liu, X Wei - Functional & Integrative Genomics, 2023 - Springer
Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer. In
recent years, cell senescence emerges as a potential therapeutic target of cancer therapy …
recent years, cell senescence emerges as a potential therapeutic target of cancer therapy …