Effect of reactive oxygen species on the endoplasmic reticulum and mitochondria during intracellular pathogen infection of mammalian cells
J Lee, CH Song - Antioxidants, 2021 - mdpi.com
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …
Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders
The 78 kDa glucose‐regulated protein (GRP78) is an endoplasmic reticulum (ER)‐resident
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …
Insights into the role of endoplasmic reticulum stress in infectious diseases
JA Choi, CH Song - Frontiers in immunology, 2020 - frontiersin.org
The endoplasmic reticulum (ER) is the major organelle in the cell for protein folding and
plays an important role in cellular functions. The unfolded protein response (UPR) is …
plays an important role in cellular functions. The unfolded protein response (UPR) is …
Herp regulates intracellular survival of Mycobacterium tuberculosis H37Ra in macrophages by regulating reactive oxygen species-mediated autophagy
SH Son, J Lee, SN Cho, JA Choi, J Kim, TD Nguyen… - Mbio, 2023 - Am Soc Microbiol
Novel treatment strategies for tuberculosis (TB), such as host-directed therapeutics, may
offer therapeutic options for patients with drug-resistant TB. Endoplasmic reticulum (ER) …
offer therapeutic options for patients with drug-resistant TB. Endoplasmic reticulum (ER) …
M1 macrophage dependent-p53 regulates the intracellular survival of mycobacteria
YJ Lim, J Lee, JA Choi, SN Cho, SH Son, SJ Kwon… - Apoptosis, 2020 - Springer
Tumor suppressor p53 is not only affects immune responses but also contributes to
antibacterial activity. However, its bactericidal function during mycobacterial infection …
antibacterial activity. However, its bactericidal function during mycobacterial infection …
Liposome-encapsulated bacillus calmette–guérin cell wall skeleton enhances antitumor efficiency for bladder cancer in vitro and in vivo via induction of amp-activated …
Simple Summary We engineered novel nanoparticles consisting of liposome-encapsulated
Bacillus Calmette–Guérin cell well skeleton (BCG-CWS) for intravesical instillation in …
Bacillus Calmette–Guérin cell well skeleton (BCG-CWS) for intravesical instillation in …
Mitofusin 2-Deficiency Suppresses Mycobacterium tuberculosis Survival in Macrophages
J Lee, JA Choi, SN Cho, SH Son, CH Song - Cells, 2019 - mdpi.com
Apoptosis is an important host defense mechanism against mycobacterial infection.
However, the molecular mechanisms regulating apoptosis during mycobacterial infection …
However, the molecular mechanisms regulating apoptosis during mycobacterial infection …
Enhancement of the antimycobacterial activity of macrophages by ajoene
Ajoene, a garlic-derived sulfur-containing compound, has broad-spectrum antimicrobial
activity. To assess the potential of ajoene for treating tuberculosis (TB), we determined …
activity. To assess the potential of ajoene for treating tuberculosis (TB), we determined …
TNF‐α‐mediated ER stress causes elimination of Mycobacterium fortuitum reservoirs by macrophage apoptosis
Mycobacterium fortuitum (MF), a rapidly growing nontuberculosis mycobacterium, is
recognized as an important human pathogen. We investigated whether the endoplasmic …
recognized as an important human pathogen. We investigated whether the endoplasmic …
Discovery and overview of Par-4
S Ganguly, R Burikhanov, S Qiu… - Tumor Suppressor Par-4 …, 2022 - Springer
Abstract Prostate apoptosis response-4 (Par-4) is a tumor suppressor that was first identified
as an immediate early gene in a differential screen for genes induced during the process of …
as an immediate early gene in a differential screen for genes induced during the process of …