Significance: Cutaneous scarring affects millions of patients worldwide and results in
significant financial and psychosocial burdens. Given the immune system's intricate …

Mastitis is a major infectious disease affecting high yielding cows in dairy herds. Because of
its economic impact and due to the animal welfare policy, the pathogenesis of this …

Background Mastitis, which affects nearly all lactating mammals including human, is
generally thought to be caused by local infection of the mammary glands. For treatment …

Interest in preclinical drug development for ovarian cancer has stimulated development of
patient-derived xenograft (PDX) or tumorgraft models. However, the unintended formation of …

Developing monoclonal antibodies (mAbs) for cancer immunotherapy is expensive and
complicated. Nanobodies are small antibodies possessing favorable pharmacological …

Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive
cancers with a very low survival rate at 5 years. The use of chemotherapeutic agents results …

Adaptive immunity has long been regarded as the major player in protection against most
fungal infections. Mounting evidence suggest however, that both innate and adaptive …

CD99 is a surface molecule expressed on various cell types including cancer cells.
Expression of CD99 on multiple myeloma is associated with CCND1-IGH fusion/t (11; 14) …

Staphylococcus aureus intramammary colonization of the mouse mammary gland induces
migration of polymorphonuclear neutrophils (PMNs) similar to that observed during bovine …

Candida activates complement via all three pathways leading to opsonisation and
anaphylaxis. The aim of the study was to investigate the influence of the terminal …