Myopia, also known as short-sightedness or near-sightedness, is a very common condition
that typically starts in childhood. Severe forms of myopia (pathologic myopia) are associated …

Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Understanding the tumor immune microenvironment (TIME) promises to be key for optimal
cancer therapy, especially in triple-negative breast cancer (TNBC). Integrating spatial …

Background Metastatic colonization is one of the critical steps in tumor metastasis. A pre-
metastatic niche is required for metastatic colonization and is determined by tumor-stroma …

One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC),
which is often diagnosed in its latter, deadly stages. The OC's high mortality and …

Oxidative stress due to imbalance between ROS production and detoxification plays a
pivotal role in determining cell fate. In response to the excessive ROS, apoptotic signaling …

Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix,
behaving as a critical mechanism in preventing adherent-independent cell growth and …

Reactive species, which mainly include reactive oxygen species (ROS), are products
generated as a consequence of metabolic reactions in the mitochondria of eukaryotic cells …

Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …