[HTML][HTML] Allosteric modulation of GPCRs: new insights and potential utility for treatment of schizophrenia and other CNS disorders

DJ Foster, PJ Conn - Neuron, 2017 - cell.com
G-protein-coupled receptors (GPCRs) play critical roles in regulating brain function. Recent
advances have greatly expanded our understanding of these receptors as complex …

The effects of medication use in transcranial direct current stimulation: a brief review

ME McLaren, NR Nissim, AJ Woods - Brain stimulation, 2018 - Elsevier
Background There has been increased interest in the potential use of transcranial direct
current stimulation (tDCS) as treatment for multiple conditions including depression, pain …

Effects of transcranial direct current stimulation (tDCS) on cognition, symptoms, and smoking in schizophrenia: a randomized controlled study

RC Smith, S Boules, S Mattiuz, M Youssef… - Schizophrenia …, 2015 - Elsevier
Schizophrenia is characterized by cognitive deficits which persist after acute symptoms have
been treated or resolved. Transcranial direct current stimulation (tDCS) has been reported to …

Modulating neural circuits with transcranial magnetic stimulation: implications for addiction treatment development

CA Hanlon, LT Dowdle, JS Henderson - Pharmacological reviews, 2018 - ASPET
Although the last 50 years of clinical and preclinical research have demonstrated that
addiction is a brain disease, we still have no neural circuit–based treatments for substance …

Potentiation of M1 muscarinic receptor reverses plasticity deficits and negative and cognitive symptoms in a schizophrenia mouse model

A Ghoshal, JM Rook, JW Dickerson, GN Roop… - …, 2016 - nature.com
Schizophrenia patients exhibit deficits in signaling of the M 1 subtype of muscarinic
acetylcholine receptor (mAChR) in the prefrontal cortex (PFC) and also display impaired …

Improving working memory in schizophrenia: Effects of 1 mA and 2 mA transcranial direct current stimulation to the left DLPFC

I Papazova, W Strube, B Becker, B Henning… - Schizophrenia …, 2018 - Elsevier
Deficits in various cognitive processes, such as working memory, are characteristic for
schizophrenia, lowering patients' functioning and quality of life. Recent research suggests …

Examining bi-anodal transcranial direct current stimulation (tDCS) over bilateral dorsolateral prefrontal cortex coupled with bilateral extracephalic references as a …

CC Chang, YC Kao, CY Chao, NS Tzeng… - Progress in Neuro …, 2020 - Elsevier
No studies have examined the efficacy of bi-anodal transcranial direct current stimulation
(tDCS) over bilateral dorsolateral prefrontal cortex (DLPFC) coupled with bilateral …

Beneficial effects of anodal transcranial direct current stimulation (tDCS) on spatial working memory in patients with schizophrenia

T Schwippel, I Papazova, W Strube, AJ Fallgatter… - European …, 2018 - Elsevier
Schizophrenia is a severe and often detrimental psychiatric disorder. The individual patients'
level of functioning is essentially determined by cognitive, particularly working memory …

Motor cortical plasticity in schizophrenia: A meta-analysis of Transcranial Magnetic Stimulation–Electromyography studies

UM Mehta, MV Thanki, J Padmanabhan… - Schizophrenia …, 2019 - Elsevier
Background Several lines of investigations converge upon aberrant synaptic plasticity as a
potential pathophysiological characteristic of schizophrenia. In vivo experiments using …

Nicotine smoking prevents the effects of frontotemporal transcranial direct current stimulation (tDCS) in hallucinating patients with schizophrenia

J Brunelin, A Hasan, F Haesebaert… - Brain …, 2015 - pubmed.ncbi.nlm.nih.gov
Nicotine Smoking Prevents the Effects of Frontotemporal Transcranial Direct Current Stimulation
(tDCS) in Hallucinating Patients With Schizophrenia Nicotine Smoking Prevents the Effects of …