Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate
immunity, the drive for the development of TLR2-targeted therapeutic treatments has …

Glycolipids constitute a major part of the cell envelope of Mycobacterium tuberculosis (Mtb).
They are potent immunomodulatory molecules recognized by several immune receptors like …

Tuberculosis (TB) remains a public health problem worldwide and is one of the deadliest
infectious diseases, only after the current COVID-19 pandemic. Despite significant advances …

Introduction Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis
(M. tb). B cells are the central mediator of the humoral response; they are responsible for …

Introduction Fungal infections are caused by a broad range of pathogenic fungi that are
found worldwide with different geographic distributions, incidences, and mortality rates …

Understanding the role of B cells in tuberculosis (TB) is crucial for developing new TB
vaccines. However, the changes in B cell immune landscapes during TB and their functional …

Sustained control of Mycobacterium tuberculosis (Mtb) infection without evidence of disease
is based on a finely tuned balance between pro-and anti-inflammatory responses. Loss of …

The underdevelopment of adjuvant discovery and diversity, compared to core vaccine
technology, is evident. On the other hand, antibiotic resistance is on the list of the top ten …

Limited data exist about the comparative immune cell population profile determined by
cytometry by time-of-flight (CyTOF) analysis between active tuberculosis (TB) and latent TB …

Objectives We investigated the expression of toll-like receptor (TLR)-4 on the cell surface of
innate and adaptive cells from patients with COVID-19 carrying the rs4986790 GG genotype …