TOPAS: an innovative proton Monte Carlo platform for research and clinical applications
Purpose: While Monte Carlo particle transport has proven useful in many areas (treatment
head design, dose calculation, shielding design, and imaging studies) and has been …
head design, dose calculation, shielding design, and imaging studies) and has been …
The TOPAS tool for particle simulation, a Monte Carlo simulation tool for physics, biology and clinical research
Purpose This paper covers recent developments and applications of the TOPAS TOol for
PArticle Simulation and presents the approaches used to disseminate TOPAS. Materials and …
PArticle Simulation and presents the approaches used to disseminate TOPAS. Materials and …
A phenomenological relative biological effectiveness (RBE) model for proton therapy based on all published in vitro cell survival data
AL McNamara, J Schuemann… - Physics in Medicine & …, 2015 - iopscience.iop.org
Proton therapy treatments are currently planned and delivered using the assumption that the
proton relative biological effectiveness (RBE) relative to photons is 1.1. This assumption …
proton relative biological effectiveness (RBE) relative to photons is 1.1. This assumption …
TOPAS-nBio: an extension to the TOPAS simulation toolkit for cellular and sub-cellular radiobiology
J Schuemann, AL McNamara… - Radiation …, 2019 - meridian.allenpress.com
The TOPAS Monte Carlo (MC) system is used in radiation therapy and medical imaging
research, having played a significant role in making Monte Carlo simulations widely …
research, having played a significant role in making Monte Carlo simulations widely …
Site-specific range uncertainties caused by dose calculation algorithms for proton therapy
The purpose of this study was to assess the possibility of introducing site-specific range
margins to replace current generic margins in proton therapy. Further, the goal was to study …
margins to replace current generic margins in proton therapy. Further, the goal was to study …
Development of a high resolution voxelised head phantom for medical physics applications
V Giacometti, S Guatelli, M Bazalova-Carter… - Physica Medica, 2017 - Elsevier
Computational anthropomorphic phantoms have become an important investigation tool for
medical imaging and dosimetry for radiotherapy and radiation protection. The development …
medical imaging and dosimetry for radiotherapy and radiation protection. The development …
Experimental validation of the TOPAS Monte Carlo system for passive scattering proton therapy
Purpose: TOPAS (TOol for PArticle Simulation) is a particle simulation code recently
developed with the specific aim of making Monte Carlo simulations user‐friendly for …
developed with the specific aim of making Monte Carlo simulations user‐friendly for …
[HTML][HTML] Mechanistic model of radiotherapy-induced lung fibrosis using coupled 3D agent-based and Monte Carlo simulations
Background Mechanistic modelling of normal tissue toxicities is unfolding as an alternative
to the phenomenological normal tissue complication probability models. The latter, currently …
to the phenomenological normal tissue complication probability models. The latter, currently …
Cellular response to proton irradiation: a simulation study with TOPAS-nBio
The cellular response to ionizing radiation continues to be of significant research interest in
cancer radiotherapy, and DNA is recognized as the critical target for most of the biologic …
cancer radiotherapy, and DNA is recognized as the critical target for most of the biologic …
Characterization and validation of a Monte Carlo code for independent dose calculation in proton therapy treatments with pencil beam scanning
F Fracchiolla, S Lorentini, L Widesott… - Physics in Medicine & …, 2015 - iopscience.iop.org
We propose a method of creating and validating a Monte Carlo (MC) model of a proton
Pencil Beam Scanning (PBS) machine using only commissioning measurements and …
Pencil Beam Scanning (PBS) machine using only commissioning measurements and …