Classical bovine spongiform encephalopathy and chronic wasting disease: two sides of the prion coin

NJ Haley, JA Richt - Animal Diseases, 2023 - Springer
Transmissible spongiform encephalopathies (TSEs) are a group of progressive and
ultimately fatal neurologic diseases of man and animals, all resulting from the propagated …

Disease phenotype of classical sheep scrapie is changed upon experimental passage through white-tailed deer

RD Kokemuller, SJ Moore, J Bian… - PLoS …, 2023 - journals.plos.org
Prion agents occur in strains that are encoded by the structure of the misfolded prion protein
(PrPSc). Prion strains can influence disease phenotype and the potential for interspecies …

Scrapie versus Chronic Wasting Disease in White-Tailed Deer

ZJ Lambert, J Bian, ED Cassmann… - Emerging Infectious …, 2024 - pmc.ncbi.nlm.nih.gov
White-tailed deer are susceptible to scrapie (WTD scrapie) after oronasal inoculation with
the classical scrapie agent from sheep. Deer affected by WTD scrapie are difficult to …