The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

Autoimmune and inflammatory uveitis are a group of potentially blinding intraocular
inflammatory diseases that arise without a known infectious trigger and are often associated …

The term uveitis encompasses a very diverse group of inflammatory ocular diseases that
cause a significant burden of legal and economic blindness. Indeed, the socioeconomic …

Certain cellular components of the eye, such as neural retina, are unable to regenerate and
replicate after destructive inflammation. Ocular immune privilege provides the eye with …

Co-inhibitory receptors (IRs) are molecules that protect host against autoimmune reactions
and maintain peripheral self-tolerance, playing an essential role in maintaining immune …

Zinc is an essential nutrient for human health. It plays key roles in maintaining protein
structure and stability, serves as catalytic factor for many enzymes, and regulates diverse …

Ischemia–reperfusion injury is a well-known pathological hallmark associated with diabetic
retinopathy, glaucoma, and other related retinopathies that ultimately can lead to visual …

Autoimmune diseases usually follow a relapsing-remitting or a chronic progressive course.
To understand the underlying immunopathogenesis we investigated experimental Lewis rat …

Background Non-infectious uveitis can cause chronic relapsing and remitting ocular
inflammation, which may require high dose systemic immunosuppression to prevent severe …

Introduction: This review represents the current in vitro, in vivo, animal and human
investigations on the roles of IL-10 in ocular inflammatory conditions. Materials and …