[HTML][HTML] Malignant mesothelioma biomarkers: from discovery to use in clinical practice for diagnosis, monitoring, screening, and treatment

J Creaney, BWS Robinson - Chest, 2017 - Elsevier
Malignant pleural mesothelioma is a highly aggressive tumor associated with asbestos
exposure. There are few effective treatment options for mesothelioma, and patients have a …

[HTML][HTML] British Thoracic Society Guideline for the investigation and management of malignant pleural mesothelioma

I Woolhouse, L Bishop, L Darlison, D De Fonseka… - Thorax, 2018 - thorax.bmj.com
Refer all patients with a chest X-ray suggestive of MPM urgently (via the 2-week wait
suspected cancer pathway in England and Wales). Consider referral for further investigation …

Screening and biosensor-based approaches for lung cancer detection

L Wang - Sensors, 2017 - mdpi.com
Early diagnosis of lung cancer helps to reduce the cancer death rate significantly. Over the
years, investigators worldwide have extensively investigated many screening modalities for …

Diagnostic value of CEA and CYFRA 21-1 tumor markers in primary lung cancer

K Okamura, K Takayama, M Izumi, T Harada… - Lung cancer, 2013 - Elsevier
Lung cancer is sometimes difficult to differentiate from benign lung diseases expressing
nodular shadow in imaging study. We assessed the diagnostic value of two commonly used …

ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma

I Opitz, A Scherpereel, T Berghmans… - European journal of …, 2020 - academic.oup.com
Abstract The European Respiratory Society (ERS)/European Society of Thoracic Surgeons
(ESTS)/European Association for Cardio-Thoracic Surgery (EACTS)/European Society for …

The combination of CA125 and NSE is useful for predicting liver metastasis of lung cancer

CF Wang, SJ Peng, RQ Liu, YJ Yu, QM Ge… - Disease …, 2020 - Wiley Online Library
Purpose. Liver metastasis is the final stage of cancer progression and is associated with
poor prognosis. Although numerous indicators have been identified as having prognostic …

Identification of miRNA-103 in the cellular fraction of human peripheral blood as a potential biomarker for malignant mesothelioma–a pilot study

DG Weber, G Johnen, O Bryk, KH Jöckel, T Brüning - PloS one, 2012 - journals.plos.org
Background To date, no biomarkers with reasonable sensitivity and specificity for the early
detection of malignant mesothelioma have been described. The use of microRNAs …

Enhancement of diagnostic performance in lung cancers by combining CEA and CA125 with autoantibodies detection

R Zang, Y Li, R Jin, X Wang, Y Lei, Y Che, Z Lu… - …, 2019 - Taylor & Francis
Objectives: Although low-dose computed tomography has been confirmed to have
meaningful diagnostic utility, lung cancer is still the leading cause of cancer-related deaths …

Prediagnostic detection of mesothelioma by circulating calretinin and mesothelin–a case-control comparison nested into a prospective cohort of asbestos-exposed …

G Johnen, K Burek, I Raiko, K Wichert, B Pesch… - Scientific reports, 2018 - nature.com
Malignant mesothelioma (MM) is strongly associated with a previous asbestos exposure. To
improve timely detection of MM in asbestos workers, better screening tools–like minimally …

Combination of MiR-103a-3p and mesothelin improves the biomarker performance of malignant mesothelioma diagnosis

DG Weber, S Casjens, G Johnen, O Bryk, I Raiko… - PloS one, 2014 - journals.plos.org
Background For the detection of malignant mesothelioma no single biomarker with
reasonable sensitivity and specificity has been described so far. Mesothelin, the most …