Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …

Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

The corporeal beauty of the neuronal cytoskeleton has captured the imagination of
generations of scientists. One of the easiest cellular structures to visualize by light …

Proper brain wiring during development is pivotal for adult brain function. Neurons display a
high degree of polarization both morphologically and functionally, and this polarization …

Neuronal polarization establishes distinct molecular structures to generate a single axon
and multiple dendrites. Studies over the past years indicate that this efficient separation is …

Retinal ganglion cell (RGC) replacement holds potential for restoring vision lost to optic
neuropathy. Transplanted RGCs must undergo neuroretinal integration to receive afferent …

Neurons are among the most morphologically complex cells. A distinction between two
compartments, axon and dendrite, generates cellular domains that differ in membrane …

Throughout the central nervous system, astrocytes adopt precisely ordered spatial
arrangements of their somata and arbors, which facilitate their many important functions …

Neurons are one of the highly polarized cells in the body. One of the fundamental issues in
neuroscience is how neurons establish their polarity; therefore, this issue fascinates many …

In a biological sense, polarity refers to the extremity of the main axis of an organelle, cell, or
organism. In neurons, morphological polarity begins with the appearance of the first neurite …