[HTML][HTML] Phage therapy: From biological mechanisms to future directions
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …
the natural predators of bacteria discovered over 100 years ago. In order to use phages …
Bacterial defences: mechanisms, evolution and antimicrobial resistance
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …
microorganisms, including competing bacteria, bacteriophages and predators. In response …
Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies
A Catalano, D Iacopetta, J Ceramella, D Scumaci… - Molecules, 2022 - mdpi.com
Multidrug resistance is a leading concern in public health. It describes a complex phenotype
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …
Phage therapy for antibiotic-resistant bacterial infections
GF Hatfull, RM Dedrick… - Annual Review of …, 2022 - annualreviews.org
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of
infectious diseases. Development of new classes of antibiotics has slowed in recent years …
infectious diseases. Development of new classes of antibiotics has slowed in recent years …
Considerations for the use of phage therapy in clinical practice
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …
renewed interest in phage therapy as an alternative or adjunct to conventional …
Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa
isolates are frequent causes of serious nosocomial infections that may compromise the …
isolates are frequent causes of serious nosocomial infections that may compromise the …
Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …
Mechanisms and clinical importance of bacteriophage resistance
JE Egido, AR Costa… - FEMS microbiology …, 2022 - academic.oup.com
We are in the midst of a golden age of uncovering defense systems against bacteriophages.
Apart from the fundamental interest in these defense systems, and revolutionary applications …
Apart from the fundamental interest in these defense systems, and revolutionary applications …
Phage therapy in the postantibiotic era
FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …
number of infections are becoming harder or almost impossible to treat, carrying high …
Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler
B Van Nieuwenhuyse, D Van der Linden… - Nature …, 2022 - nature.com
Post-operative bacterial infections are a leading cause of mortality and morbidity after
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …